184297-05-0

Basic information

• Product Name: Thiocarbonic acid O-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl] ester O-phenyl ester
• Synonyms: Thiocarbonic acid O-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl] ester O-phenyl ester
• CAS NO: 184297-05-0
• Molecular Weight: 542.694
• Mol File: 184297-05-0.mol

Chemical Properties

• CAS DataBase Reference: Thiocarbonic acid O-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl] ester O-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Thiocarbonic acid O-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl] ester O-phenyl ester(184297-05-0)
• EPA Substance Registry System: Thiocarbonic acid O-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl] ester O-phenyl ester(184297-05-0)

Safety Data

• Hazardous Substances Data: 184297-05-0(Hazardous Substances Data)

Upstream product

• 184296-98-8 (2R,3S,4R,5R)-5-(6-Amino-purin-9-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-ol 
• 1005-56-7 phenylcarbonochloridothioate 
• 58699-61-9 2'-Azido-2'-deoxyadenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Relevant articles and documents

Nucleic acid related compounds. 91. Biomimetic reactions are in harmony with loss of 2'-substituents as free radicals (not anions) during mechanism-based inactivation of ribonucleotide reductases. Differential interactions of azide, halogen, and alkylthio

The initial step in the mechanism-based inactivation of ribonucleotide reductases by 2'-chloro-2'deoxynucleotides is abstraction of H3' by a proximal free radical on the enzyme. The C3' radical is postulated to undergo spontaneous loss of chloride, and th