1843-50-1Relevant academic research and scientific papers
A convenient synthesis of chiral 2-methylenebenzo[e][1,4]diazepin-5-ones via a one-pot reductive cyclodehydration with retention of chirality
Sorra, Kumaraswamy,Lai, Chin-Hung,Feng, Chun-Yen,Wu, Yang-Chang,Pusuluri, Srinivas,Mukkanti, Khagga,Chuang, Ta-Hsien
, p. 4842 - 4844 (2016)
Total synthesis of optically pure (+)-Fuligocandin A from L-proline has been achieved in 29% overall yield. The key step, one-pot reductive cyclodehydration of the chiral 2-nitrophenyl-1,3-dicarbonyl compound, proceeds with >98% retention of configuration
