18433-52-8

Upstream product

• 7396-77-2 N,N'-bis(3-methoxysalicylidene)ethylenediamine 
• 6147-53-1 cobalt(II) diacetate tetrahydrate 
• 78166-97-9 2-hydroxy-3-methoxybenzaldehyde sodium salt 
• 18433-55-1 bis(2-hydroxy-3-methoxy-benzylidene)-ethylenediamine cobalt(II) monohydrate 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Relevant academic research and scientific papers

Syntheses of the Carotane-type Terpenoids (+)-Schisanwilsonene A and (+)-Tormesol via a Two-Stage Approach

Stereoselective syntheses of terpenoids in a more efficient manner have been a long-term pursuit for synthetic chemists. Herein we describe the two-step, enantiospecific and protecting-group-free synthesis of (+)-schisanwilsonene A from a carotane compound, which was produced in E. coli. We also completed the first enantiomeric synthesis of (+)-tormesol in five steps. The two-stage strategy offers a step- and redox-economical approach to prepare terpene natural products and their analogues.