184376-53-2Relevant academic research and scientific papers
Synthesis and biological evaluation of 2β,3α-(substituted phenyl)nortropanes as potential norepinephrine transporter imaging agents
Zeng, Fanxing,Stehouwer, Jeffrey S.,Jarkas, Nachwa,Voll, Ronald J.,Williams, Larry,Camp, Vernon M.,Votaw, John R.,Owens, Michael J.,Kilts, Clinton D.,Nemeroff, Charles B.,Goodman, Mark M.
, p. 3044 - 3047 (2008/02/05)
A series of 2β,3α-(substituted phenyl)nortropanes was synthesized and evaluated in vitro for human monoamine transporters. All compounds studied in this series exhibited nanomolar potency for the norepinephrine transporter (NET). Radiolabeling and nonhuma
Dopamine transporter imaging ligand
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Page column 5-6, (2010/01/30)
The 3α isomer of RTI-55, RTI-352, is an effective in vivo binding ligand that reflects greater selectivity for the dopamine transporter than is observed with RTI-55. In addition, there is also a more rapid achievement of apparent equilibrium in the striat
