18456-85-4Relevant academic research and scientific papers
REGIOSELECTIVE ALKYLATION OF DIANIONS OF CYCLIC 1,3-DIKETONES VIA THEIR MONODIMETHYLHYDRAZONES. SYNTHESIS OF C-4 SUBSTITUTED 1,3-DIKETONES
Demir, Ayhan S.,Enders, Dieter
, p. 1705 - 1708 (2007/10/02)
Cyclic 1,3-diketones are transformed into the corresponding monodimethylhydrazones, which can be alkylated regioselectively at C-4 via dianions with various alkyl halides.
Direct 4-Alkylation of 1,3-Cyclohexanediones via Dianionic Species
Berry, Nicola M.,Darey, Mark C. P.,Harwood, Laurence M.
, p. 476 - 480 (2007/10/02)
1,3-Cyclohexanediones are directly alkylated at the 4 position via dianionic species generated at -78 deg C using lithium diisopropylamine/hexamethylphosphoric triamide.Acetylation of the reaction products at room temperature yields the 3-acetoxy-6-alkylc
ORGANIC REACTIONS AT HIGH PRESSURE. MICHAEL ADDITION OF ACTIVATED ACYCLIC DONORS WITH β,β-DISUBSTITUTED ENONE ACCEPTORS.
Dauben, William G.,Gerdes, John M.
, p. 3841 - 3844 (2007/10/02)
High pressure, 15 kbar (1.5 GPa) Michael additions of doubly activated acyclic donors to sterically hindered enone acceptors with 1,5-diazabicyclonon-5-ene in acetonitrile affords Michael adducts in 42-82percent yield.
