184580-92-5Relevant academic research and scientific papers
Synthesis of oxadiazole-2-oxide analogues as potential antischistosomal agents
Rai, Ganesha,Thomas, Craig J.,Leister, William,Maloney, David J.
scheme or table, p. 1710 - 1713 (2009/07/05)
The synthesis of several 1,2,5-oxadiazole-2-oxide (Furoxan) analogues is described herein. These compounds were prepared in an effort to probe the SAR around the phenyl substituent and oxadiazole core for our studies toward thioredoxin-glutathione reductase (TGR) inhibition and antischistosomal activity.
151. Synthesis and structural characterization of the trimeric furoxan (= furazan 2-oxide) system, a new potent vasodilating moiety
Gasco, Andrea M.,Cena, Clara,Di Stilo, Antonella,Ermondi, Giuseppe,Medana, Claudio,Gasco, Alberto
, p. 1803 - 1817 (2007/10/03)
The synthesis, structural characterization, and NO donor properties of a series of terfuroxan (= terfurazan trioxide) derivatives 1a-h and 2a-j are reported (Schemes 1 and 2). Structural assignments were confirmed principally by mass and 13C- a
