184646-10-4Relevant academic research and scientific papers
Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design
Prokai-Tatrai, Katalin,Prokai, Laszlo,Bodor, Nicholas
, p. 4775 - 4782 (1996)
A brain-targeted chemical delivery system (CDS) based on retrometabolic drug design was applied to a Leu-enkephalin analogue, Tyr-D-Ala-Gly-Phe-D- Leu (DADLE). The molecular architecture of the peptide CDS disguises its peptide nature from neuropeptide-de
