184681-54-7Relevant articles and documents
Iron(III) chloride-catalyzed convenient one-pot synthesis of β-acetamido carbonyl compounds
Khan, Abu T.,Parvin, Tasneem,Choudhury, Lokman H.
, p. 5593 - 5601 (2007)
A one-pot multi-component reaction of aldehydes, enolizable ketones or 1,3-dicarbonyls, acetonitrile/benzonitrile, and acetyl chloride is described for the preparation of β-acetamido carbonyl compounds using FeCl3·6H2O as a mild, inexpensive, and highly efficient catalyst. The effect of substrate as well as substituent for multi-component reaction versus Knoevenagel condensation is also illustrated. The key features of this methodology are operational simplicity, mild reaction conditions, and good yields.
Sila-substituted 1,4-dihydropyridine derivatives and their medicinal use
-
, (2008/06/13)
The invention provides sila-substituted 1,4-dihydropyridine derivatives useful as medicament which influence the circulation. Also included in the invention are methods for the procurement of said derivatives, compositions containing said derivatives and