184698-41-7

Basic information

• Product Name: 2H-Pyran-4-carboxylicacid,4-aminotetrahydro-,methylester(9CI)
• Synonyms: 2H-Pyran-4-carboxylicacid,4-aminotetrahydro-,methylester(9CI);4-Aminotetrahydropyran-4-carboxylic acid methyl ester;Methyl 4-aminotetrahydropyran-4-carboxylate hydrochloride , 95%;Methyl 4-aMinotetrahydro-2H-pyran-4-carboxylate;4-AMinotetrahydro-2H-pyran-4-carboxylic acid Methyl ester;Methyl 4-aMinotetrahydro-2H-pyran-4-carboxylate hydrochloride;Methyl 4-AMinotetrahydropyran-4-carboxylate;methyl 4-aminooxane-4-carboxylate
• CAS NO: 184698-41-7
• Molecular Formula: C₇H₁₃NO₃
• Molecular Weight: 159.184
• Product Categories: CARBOXYLICESTER;pharmacetical
• Mol File: 184698-41-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 223.5°Cat760mmHg
• Flash Point: 87.8°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 0.096mmHg at 25°C
• Refractive Index: 1.466
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 6.24±0.20(Predicted)
• CAS DataBase Reference: 2H-Pyran-4-carboxylicacid,4-aminotetrahydro-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-4-carboxylicacid,4-aminotetrahydro-,methylester(9CI)(184698-41-7)
• EPA Substance Registry System: 2H-Pyran-4-carboxylicacid,4-aminotetrahydro-,methylester(9CI)(184698-41-7)

Safety Data

• Hazardous Substances Data: 184698-41-7(Hazardous Substances Data)

Usage

General Description

2H-Pyran-4-carboxylic acid, 4-aminotetrahydro-, methyl ester (9CI) is a chemical compound with the molecular formula C8H13NO3. It is a methyl ester derivative of 4-aminotetrahydropyran-4-carboxylic acid and belongs to the class of pyran carboxylic acids. 2H-Pyran-4-carboxylicacid,4-aminotetrahydro-,methylester(9CI) is used in various chemical and pharmaceutical applications, including as a building block for the synthesis of other organic compounds. It is also used as a research tool in the development of new drugs and chemicals. The chemical properties and potential uses of 2H-Pyran-4-carboxylic acid, 4-aminotetrahydro-, methyl ester (9CI) make it a valuable and versatile chemical in the field of organic chemistry.

InChI:InChI=1/C7H13NO3/c1-10-6(9)7(8)2-4-11-5-3-7/h2-5,8H2,1H3

Upstream product

• 67-56-1 methanol 
• 39124-20-4 4-aminotetrahydro-2H-pyran-4-carboxylic acid 
• 50289-12-8 4-amino-tetrahydro-2H-pyran-4-carbonitrile 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 

Downstream Products

• 1326318-35-7 C₁₅H₁₆BrCl₂NO₄ 
• 1326318-10-8 C₂₅H₃₀ClNO₄ 
• 1326317-99-0 C₂₇H₃₀ClNO₅ 
• 1326317-95-6 C₂₈H₃₂ClNO₄ 
• 1326317-71-8 C₂₀H₁₆Cl₃NO₃ 
• 1326317-70-7 C₂₄H₂₆ClNO₃ 
• 1326318-32-4 C₁₄H₁₂BrCl₂NO₃ 
• 720706-20-7 (4-aminotetrahydro-2H-pyran-4-yl)methanol 

Relevant articles and documents

COMPOUNDS

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds of substituted or unsubstituted cyclylamine derivatives as shown in formulas (1).

PYRAZOLE COMPOUNDS HAVING CANNABINOID RECEPTOR (CB1) ANTAGONIZING ACTIVITY

The present invention relates to a pyrazole compound having potent CB1-antagonizing activity, having the following formula [I]: wherein R1 and R2 are the same or different and an optionally substituted aryl group etc., R3 is an alkyl group etc., E is one of the following groups of the formula (i) to (iv): Q1 is a single bond, an alkylene group or a group of the formula: -N(R7)-, R7 is a hydrogen atom or an alkyl group, Q2 is a single bond, an oxygen atom or an alkylene group, R4 is a cycloalkyl group, a group of the formula: -N(R5)(R6) etc., one of R5 and R6 is a hydrogen atom or an alkyl group and the other is an alkyl group, a group of the formula: -N(R8)(R9) etc., D is an oxygen atom etc., RA1 is an amino group etc., RA2 is an optionally substituted aliphatic heterocyclic group, R is an alkyl group optionally substituted by one to three halogen atom(s) etc., one of R8 and R9 is a hydrogen atom or an alkyl group and the other is an alkyl group etc., or a pharmaceutically acceptable salt thereof.