18474-57-2 Usage
Description
4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID is an organic compound with the molecular formula C10H9NO2. It is a derivative of indole-2-carboxylic acid, featuring a methyl group at the 4th position. 4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID has potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID is used as a key intermediate in the synthesis of novel indole-2-carboxamides. These compounds have shown activity against the hepatitis B virus (HBV), making them valuable in the development of new antiviral drugs.
Used in Antiviral Applications:
4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID is used as a building block for creating new antiviral agents, specifically targeting the hepatitis B virus. Its incorporation into indole-2-carboxamides enhances their ability to combat HBV, offering a potential therapeutic solution for patients suffering from this viral infection.
Check Digit Verification of cas no
The CAS Registry Mumber 18474-57-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,7 and 4 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18474-57:
(7*1)+(6*8)+(5*4)+(4*7)+(3*4)+(2*5)+(1*7)=132
132 % 10 = 2
So 18474-57-2 is a valid CAS Registry Number.
18474-57-2Relevant articles and documents
Indole derivatives as inhibitors or factor Xa
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, (2010/11/29)
The present invention relates to the inhibition of blood clotting proteins, and more particularly, to indole derivatives of formula (I), in which R1a, R1b, R1cR1d, R2, R3, R4and A are defined as indicated in the claims. The compounds of formula (I) are inhibitors of the blood clotting enzyme factor Xa. The invention also relates to processes for the preparation of the compounds of formula (I), to methods of inhibiting factor Xa activity and of inhibiting blood clotting, to use of the compounds of formula (I) in the treatment and prophylaxis of diseases which can be cured or prevented by the inhibition of factor Xa activity such as thromboembolic diseases, and to the use of the compounds of formula (I) in the preparation of medicaments to be applied in such diseases. The invention further relates to compositions containing a compound of formula (I) in admixture or otherwise in association with an inert carrier, in particular pharmaceutical compositions containing a compound of formula (I) together with pharmaceutically acceptable carrier substances and/or auxiliary substances.
