184779-27-9

Upstream product

• 20730-58-9 2-(2-Methoxyphenoxy)propanedioic acid diethyl ester 
• 6292-59-7 4-tert-butylbenzenesulphonamide 
• 179401-12-8 4,6-dichloro-5-(2-methoxy-phenoxy)-2-methylsulfanyl-pyrimidine 
• 184779-25-7 4-tert-butyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-methylsulfanyl-pyrimidin-4-yl]-benzenesulfonamide 
• 184779-24-6 4,6-dihydroxy-5-(2-methoxyphenoxy)-2-methylthiopyrimidine 
• 184778-95-8 N-{6-[2-(5-bromopyrimidin-2-yloxy)ethoxy]-5-(2-methoxyphenoxy)-2-methylthiopyrimidin-4-yl}-4-tert-butylbenzene-sulfonamide 
• 184779-26-8 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-methylthiopyrimidin-4-yl]-benzenesulfonamide 

Relevant academic research and scientific papers

Modifications and structure-activity relationships at the 2-position of 4-sulfonamidopyrimidine derivatives as potent endothelin antagonists

To improve water solubility and to study structure-activity relationships, we modified the structure of the pyrimidine nucleus of each of a series of potent ETA antagonists, 3a and 4a, at the 2-position. In a previous study, each of these antag

Sulfonamide derivative and process for preparing the same

Novel sulfonamide derivatives of the formula ?I!: STR1 wherein Ring A and Ring B are substituted or unsubstituted monocyclic, bicyclic or tricyclic hydrocarbon, or substituted or unsubstituted heterocyclic group, Q is single bond, --O--, --S--, --SO--, --