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1,2-Dihydro-2-methyl-3H-indazol-3-one, also known as DIMIO, is a heterocyclic chemical compound belonging to the indazole class with the molecular formula C9H8N2O. DIMIO is characterized by its yellow crystalline solid appearance and its solubility in organic solvents but not in water. It is a significant reactant in the synthesis of pharmaceutical and agrochemical compounds and has been the subject of research for its potential biological and pharmacological properties, such as enzyme inhibition and anticancer activity.

1848-40-4

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1848-40-4 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1,2-Dihydro-2-methyl-3H-indazol-3-one is used as a reactant in the synthesis of various pharmaceutical and agrochemical compounds due to its chemical reactivity and structural properties that can be incorporated into a range of molecules with therapeutic or pesticidal potential.
Used in Medicinal Chemistry Research:
DIMIO is used as a subject of study in medicinal chemistry for its potential biological and pharmacological properties. Researchers are interested in its ability to inhibit certain enzymes, which could lead to the development of new drugs targeting specific biochemical pathways.
Used in Drug Discovery:
In the field of drug discovery, 1,2-Dihydro-2-methyl-3H-indazol-3-one is used as a starting point for the development of new therapeutic agents. Its potential as an anticancer agent is of particular interest, as it may contribute to the creation of novel cancer treatments by targeting specific cellular mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 1848-40-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,4 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1848-40:
(6*1)+(5*8)+(4*4)+(3*8)+(2*4)+(1*0)=94
94 % 10 = 4
So 1848-40-4 is a valid CAS Registry Number.

1848-40-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methyl-1H-indazol-3-one

1.2 Other means of identification

Product number -
Other names 2-Methyl-1,2-dihydro-3H-indazol-3-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1848-40-4 SDS

1848-40-4Relevant academic research and scientific papers

Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug

Vega, María Celeste,Rolón, Miriam,Montero-Torres, Alina,Fonseca-Berzal, Cristina,Escario, José Antonio,Gómez-Barrio, Alicia,Gálvez, Jorge,Marrero-Ponce, Yovani,Arán, Vicente J.

, p. 214 - 227 (2013/02/23)

Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and benznidazole, is far from satisfactory and therefore the development of new antichagasic compounds remains an important goal. On the basis of antichagasic properties previously

Hypolipidemic Activity of Phthalimide Derivatives. 7. Structure-Activity Studies of Indazolone Analogues

Wyrick, Steven D.,Voorstad, P. Josee,Cocolas, George,Hall, Iris H.

, p. 768 - 772 (2007/10/02)

The apparent benefit of limiting serum cholesterol and triglyceride levels either by dietary restriction or drug therapy has prompted work in our laboratories toward development of a suitable antihyperlipidemic agent.We have demonstrated the antihyperlipi

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