1848-73-3

Usage

General Description

1H-Imidazol-2-amine, N-(4-chlorophenyl)-4,5-dihydro- is a chemical compound with the molecular formula C9H11ClN2. It is a derivative of imidazole, and its structure contains a secondary amine group and a 4-chlorophenyl substituent. 1H-Imidazol-2-amine, N-(4-chlorophenyl)-4,5-dihydro- is reported to have potential pharmaceutical applications, particularly in the treatment of various medical conditions. The 4,5-dihydro- derivative suggests that it is a reduced form of the parent compound, imidazol-2-amine, which may indicate different chemical and biological properties. Further research and studies may be warranted to fully understand the potential uses and effects of this chemical.

Upstream product

• 33142-01-7 dimethyl N-(4-chlorophenyl)carbonimidodithioate 
• 107-15-3 ethylenediamine 
• 106-47-8 4-chloro-aniline 
• 1286218-32-3 amino(4-chlorophenylimino)methanesulfonic acid 
• 2521-24-6 4-chlorothiobenzamide 
• 705-69-1 N-(4-chlorophenyl)-S-methyldithiocarbamate 
• 2131-55-7 4-Chlorophenyl isothiocyanate 

Relevant academic research and scientific papers

Efficient synthesis of 2-arylamino-2-imidazolines and 2-aminobenzimidazoles with aminoiminomethanesulfonic acid derivatives

A highly efficient synthesis of 2-arylamino-2-imidazolines and 2-aminobenzimidazoles from aminoiminomethanesulfonic acid derivatives is described. The method is simple and practical, generating imidazoline and benzimidazoline derivatives in excellent isolated yields.

The synthesis and antimicrobial activity of some new methyl N-arylthiocarbamates, dimethyl N-aryldithiocarbonimidates and 2-arylamino-2-imidazolines

Methyl N-arylthiocarbamates (2a-d) and dimethyl N-aryldithiocarbonimidates (2e-i) were synthesized from the reaction of aromatic amines with carbon disulfide and methyl iodide and NaOH in various quantitative amounts. 2-Arylamino-2-imidazolines (3a-i) wer

Microwave-assisted from synthesis of 2-arylamino-2-imidazolines on a solid support

An efficient synthesis of 2-arylamino-2-imidazolines from dimethyl N-aryldithioimidocarbonates and ethylenediamine on solid support under microwave irradiation has been developed. The reaction time has been reduced from hours to minutes with improved yiel

The efficient synthesis of 2-arylamino-2-imidazolines, 2-heteroaryl- substituted benzimidazoles, and their morpholin-4-ylmethyl derivatives

2-Heteroaryl-substituted 1H-benzimidazoles were synthesized in good yields by heating the HSO3 adducts of heteroaromatic aldehydes with o-phenylenediamine in DMF under reflux. This procedure is more general and shorter than earlier methods. 2-Arylamino-2-imidazolines were prepared by heating dimethyl aryldithioimidocarbonates and ethylenediamine under reflux. The imine-enamine tautomerization of 2-arylamino-2-imidazolines was investigated by means of 1H-NMR spectroscopy. Morpholin-4-ylmethyl derivatives of the benzimidazole and imidazoline products were synthesized regioselectively by treatment with morpholine and formaldehyde.