184833-58-7

Upstream product

• 75-11-6 diiodomethane 
• 184833-17-8 (2E,7E)-2,5,5,8-tetramethyl-9-(t-butyldiphenylsilyloxy)-2,7-nonadien-1-ol 
• 67402-86-2 3,3-dimethylglutardialdehyde 
• 184833-83-8 (2E,7E)-2,5,5,8-tetramethyl-nona-2,7-dien-1,9-dial 
• 184833-85-0 (2E,7E)-2,5,5,8-tetramethyl-nona-2,7-dien-1,9-diol 
• 17804-59-0 diethyl 3,3-dimethylglutarate 
• 66606-40-4 4,4-dimethylcyclopentane-1,2-diol 
• 54851-48-8 ((4,4-dimethylcyclopent-1-ene-1,2-diyl)bis(oxy))bis(trimethylsilane) 
• 54639-78-0 2-hydroxy-4,4-dimethylcyclopentan-1-one 

Downstream Products

• 199997-07-4 (2S,3S,7E)-2,5,5,8-tetramethyl-2,3-methano-9-(t-butyldiphenylsilyloxy)-7-nonen-1-al 
• 199997-09-6 ethyl (4S,5S,9E)-3-oxo-4,7,7,10-tetramethyl-4,5-methano-11-(t-butyldiphenylsilyloxy)-9-nonenoate 
• 199997-08-5 ethyl (3RS,4S,5S,9E)-3-hydroxy-4,7,7,10-tetramethyl-4,5-methano-11-(t-butyldiphenylsilyloxy)-9-nonenoate 
• 71493-03-3 (+)-Bicyclohumulenone 

Relevant academic research and scientific papers

The chemo- and enantioselective cyclopropanation of polyenes: Chiral auxiliary vs chiral reagent-based approach

The chemo- and enantioselective cyclopropanation of allylic alcohols containing additional olefins was investigated using the dioxaborolane-derived reagent. High chemo- and enantioselectivities were usually observed if a mixture of the chiral dioxaborolane ligand/allylic alcohol was treated with a solution of Zn(CH2I)2·DME complex.

Application of the chemo- and enantioselective cyclopropanation of polyenes to the total synthesis of (+)-bicyclohumulenone

The chemo- and enantioselective cyclopropanation of a monoprotected bis(allylic alcohol) using a chiral dioxaborolane- derived ligand and Zn(CH2I)2 was used as a key step in the total synthesis of (+)-bicyclohumulenone. The synthesis