184834-44-4Relevant academic research and scientific papers
The preparation of L,L-aspartame citric amide
Katritzky, Alan R.,Fang, Yunfeng,Prakash, Indra
, p. 675 - 677 (2007/10/03)
Mono-substituted L,L-aspartame citric amide 1 was prepared via coupling L,L-α-BMAP 3 with 1,2-dibenzyl citrate 2 prepared from selective hydrolysis of tribenzyl citrate 5.
Total synthesis of the siderophore vibrioferrin
Takeuchi, Yasuo,Akiyama, Teruaki,Harayama, Takashi
, p. 459 - 460 (2007/10/03)
Total synthesis of vibrioferrin (1), a siderophore, was achieved via chiral dibenzyl citrate separated by optical resolution. It was elucidated that the configuration of the citrate moiety of vibrio-ferrin was R.
Synthesis and siderophore activity of vibrioferrin and one of its diastereomeric isomers
Takeuchi, Yasuo,Nagao, Yoshiyuki,Toma, Kyoko,Yoshikawa, Yumiko,Akiyama, Teruaki,Nishioka, Hiromi,Abe, Hitoshi,Harayama, Takashi,Yamamoto, Shigeo
, p. 1284 - 1287 (2007/10/03)
Total synthesis of vibrioferrin (1), a siderophore, was achieved via a chiral dibenzyl citrate obtained by optical resolution. The citrate moiety of vibrioferrin was determined to have the R configuration and one of the diastereomeric isomers (1b) of 1 did not exhibit siderophore activity.
Isosteres of nucleoside triphosphates
Weaver, Richard,Gilbert, Ian H.,Mahmood, Naheed,Balzarini, Jan
, p. 2405 - 2410 (2007/10/03)
This paper describes the design and synthesis of lipophilic isosteres of nucleoside triphosphates as potential inhibitors of HIV reverse transcriptase. The isosteric replacement of the triphosphate group is a modification of the citrate group.
