184839-57-4Relevant academic research and scientific papers
Aldol-cyclization reaction sequence for the synthesis of tetrahydrofurans
Calter, Michael A.,Sugathapala, Priyantha M.,Zhu, Cheng
, p. 3837 - 3840 (2007/10/03)
The aldol reactions of α-diazo-β-ketoesters with a variety of aldehydes produced adducts which underwent Rh(II)-catalyzed O-H insertion reaction to yield highly substituted tetrahydrofurans. Alkylation and decarboxylation of these tetrahydrofurans formed a wide variety of tetrahydrofuran structures.
Annelation of aromatic oxo compounds
Karady, Sandor,Amato, Joseph S.,Reamer, Robert A.,Weinstock, Leonard M.
, p. 8277 - 8280 (2007/10/03)
The silyl enol ether of α-diazoacetoacetate is used for the annelation of aromatic oxo compounds. The method involves condensation with the oxo compound in the presence of TiCl4 followed by rhodium octanoate-catalyzed ring closure to afford fur
