184845-01-0

Basic information

• Product Name: C-(1-Benzyl-4-trifluoromethyl-pyrrolidin-3-yl)-methylamine
• Synonyms: C-(1-Benzyl-4-trifluoromethyl-pyrrolidin-3-yl)-methylamine
• CAS NO: 184845-01-0
• Molecular Formula: C₁₃H₁₇F₃N₂
• Molecular Weight: 258.28
• Mol File: 184845-01-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 288.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.196±0.06 g/cm3(Predicted)
• PKA: 10.12±0.29(Predicted)
• CAS DataBase Reference: C-(1-Benzyl-4-trifluoromethyl-pyrrolidin-3-yl)-methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: C-(1-Benzyl-4-trifluoromethyl-pyrrolidin-3-yl)-methylamine(184845-01-0)
• EPA Substance Registry System: C-(1-Benzyl-4-trifluoromethyl-pyrrolidin-3-yl)-methylamine(184845-01-0)

Safety Data

• Hazardous Substances Data: 184845-01-0(Hazardous Substances Data)

Upstream product

• 184844-93-7 (3S,4S)-1-Benzyl-4-trifluoromethyl-pyrrolidine-3-carboxylic acid 
• 169750-31-6 (3S,4S)-1-Benzyl-4-trifluoromethyl-pyrrolidine-3-carboxylic acid 
• 152188-51-7 ethyl (+/-)-(3R,4R)-1-benzyl-4-(trifluoromethyl)pyrrolidine-3-carboxylate 
• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 
• 184845-03-2 (3S,4S)-1-Benzyl-4-trifluoromethyl-pyrrolidine-3-carboxylic acid amide 

Downstream Products

• 184845-00-9 ((3R,4S)-1-Benzyl-4-trifluoromethyl-pyrrolidin-3-ylmethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Synthesis and antibacterial activity of novel 7-(3-substituted-3 or 4- trifluoromethyl-1-pyrrolidinyl)-8-methoxyfluoroquinolones

The titled compounds were synthesized and evaluated for in vitro antibacterial activity. The (3R,4S)3-aminomethyl-4-trifluoromethyl derivative (S-34109) was confirmed to be optimal because of its superior activity against quinolone and methicillin-resistant Staphyrococcus aureus and low side effect potential.