184847-74-3

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 184847-62-9 2-{3-[((S)-2-Benzyloxycarbonylamino-3-phenyl-propyl)-tert-butoxycarbonyl-amino]-2-oxo-propyl}-malonic acid dimethyl ester 
• 184847-58-3 [((S)-2-Benzyloxycarbonylamino-3-phenyl-propyl)-tert-butoxycarbonyl-amino]-acetic acid 
• 128421-87-4 Z-PheΨGly-OMe 
• 59830-60-3 benzyl (1S)-(1-formyl-2-phenylethyl)carbamate 
• 184847-60-7 {(S)-1-Benzyl-2-[tert-butoxycarbonyl-(3-chloro-2-oxo-propyl)-amino]-ethyl}-carbamic acid benzyl ester 
• 184847-56-1 [((S)-2-Benzyloxycarbonylamino-3-phenyl-propyl)-tert-butoxycarbonyl-amino]-acetic acid methyl ester 

Relevant academic research and scientific papers

Bicyclic lactams as templates for peptidomimetics. Studies on stereoselective synthetic routes to 6-oxoperhydropyrrolo[1,2-α]pyrazines

The synthesis of 4,7,7-trisubstituted 6-oxoperhydropyrrolo[1,2-α]pyrazines, as spacer templates for peptidomimetics, from the corresponding 3,6-dioxo analogues is described using different reduction methods. An alternative approach, based on the intramolecular reductive amination of 4-ketodiesters derived from Ψ[CH2NH] pseudodipeptides and subsequent γ-lactamization, was also used for the stereoselective preparation of these templates.