1849-80-5

Basic information

• Product Name: 2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine
• Synonyms: N-{2-[4-(aminomethyl)phenoxy]ethyl}-N,N-diethylamine
• CAS NO: 1849-80-5
• Molecular Formula: C₁₃H₂₂N₂O
• Molecular Weight: 222.3266
• Mol File: 1849-80-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 336.3°C at 760 mmHg
• Flash Point: 157.2°C
• Density: 0.996g/cm³
• Vapor Pressure: 0.000113mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: 2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine(1849-80-5)
• EPA Substance Registry System: 2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine(1849-80-5)

Safety Data

• Hazardous Substances Data: 1849-80-5(Hazardous Substances Data)

Usage

General Description

2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine is a chemical compound with the formula C14H24N2O. It is a derivative of diethylethanamine, containing a phenoxy group with an aminomethyl substituent at the 4-position. 2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine has potential applications in the pharmaceutical and chemical industries as it may exhibit biological activity or be used as a building block in the synthesis of other compounds. The full understanding of its properties and potential uses would require further study and experimentation.

Upstream product

• 49773-11-7 N-[2-(4-cyanophenoxy)-ethyl]-diethylamine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 100-35-6 2-(diethylamino)ethyl chloride 
• 15182-94-2 4-[2-(diethylamino)ethoxy]benzaldehyde 

Downstream Products

• 1073637-68-9 N-(4-diethylaminoethoxybenzyl)benzene-1,4-bis(sulfonamide) 

Relevant articles and documents

Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII

4-Sulfamoyl-N-(3-morpholinopropyl)benzamide (I-1), N-(3-morpholinopropyl)benzene-1,4-disulfonamide (I-2) and N-(4-diethylaminoethoxybenzyl)benzene-1,4-bis(sulfonamide (I-3), were prepared and assayed as inhibitors of four carbonic anhydrase (CA) isoenzyme

SUBSITUTED SULPHONAMIDES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION COMPRISING THEREOF AND THEIR USE

Substituted sulphonamides having the general formula (I) and salts, hydrates and solvates thereof were prepared and described, wherein R1 isCO or SO2 and R2 is NH or O and where R represents linear or cyclic aliphatic chain and n represents number of linking aliphatic chain carbons (n can be 0, 1, 2 or 3), which are useful in the manufacture of the medicaments due to the carboanhydrase inhibition. These compounds are prepared by nucleophilic reaction of an amine with 4-sulfamoylbenzenesulphonyl chloride in the presence of triethylamine excess in tetrahydrofurane or in ether at temperature 0 to 20 °C. The compounds show an antiglaucomatic activity.