1849-80-5

Usage

General Description

2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine is a chemical compound with the formula C14H24N2O. It is a derivative of diethylethanamine, containing a phenoxy group with an aminomethyl substituent at the 4-position. 2-[4-(aminomethyl)phenoxy]-N,N-diethylethanamine has potential applications in the pharmaceutical and chemical industries as it may exhibit biological activity or be used as a building block in the synthesis of other compounds. The full understanding of its properties and potential uses would require further study and experimentation.

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 100-35-6 2-(diethylamino)ethyl chloride 
• 15182-94-2 4-[2-(diethylamino)ethoxy]benzaldehyde 
• 49773-11-7 N-[2-(4-cyanophenoxy)-ethyl]-diethylamine 

Downstream Products

• 1073637-68-9 N-(4-diethylaminoethoxybenzyl)benzene-1,4-bis(sulfonamide) 

Relevant academic research and scientific papers

Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII

4-Sulfamoyl-N-(3-morpholinopropyl)benzamide (I-1), N-(3-morpholinopropyl)benzene-1,4-disulfonamide (I-2) and N-(4-diethylaminoethoxybenzyl)benzene-1,4-bis(sulfonamide (I-3), were prepared and assayed as inhibitors of four carbonic anhydrase (CA) isoenzyme

TROPANE COMPOUNDS

A compound according to Formula I or II: (I) or (II) wherein R1, R1b, R2, L1, and L2 and L2b are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.

SUBSITUTED SULPHONAMIDES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION COMPRISING THEREOF AND THEIR USE

Substituted sulphonamides having the general formula (I) and salts, hydrates and solvates thereof were prepared and described, wherein R1 isCO or SO2 and R2 is NH or O and where R represents linear or cyclic aliphatic chain and n represents number of linking aliphatic chain carbons (n can be 0, 1, 2 or 3), which are useful in the manufacture of the medicaments due to the carboanhydrase inhibition. These compounds are prepared by nucleophilic reaction of an amine with 4-sulfamoylbenzenesulphonyl chloride in the presence of triethylamine excess in tetrahydrofurane or in ether at temperature 0 to 20 °C. The compounds show an antiglaucomatic activity.

Bicyclic nitrogen heterocycles

Amino-substituted dihydropyrimido[4,5-d]pyrimidinones of the formula in which R1 represents hydrogen, lower alkyl, aryl, aryl-lower alkyl, heteroaryl, heteroaryl-lower alkyl, lower cycloalkyl or lower cycloalkyl-lower alkyl, R2 represents lower alkyl, aryl, aryl-lower alkyl, heteroaryl, heteroaryl-lower alkyl, lower cycloalkyl or lower cycloalkyl-lower alkyl, and R3 represents hydrogen, lower alkyl, aryl, aryl-lower alkyl, heteroaryl, heteroaryl-lower alkyl, lower cycloalkyl, lower cycloalkenyl or lower cycloalkyl-lower alkyl, and pharmaceutically acceptable salts thereof are protein kinase inhibitors. They can be used in the treatment or prophylaxis of inflammatory, immunological, oncological, bronchopulmonary, dermatological and cardiovascular disorders, in the treatment of asthma, central nervous system disorders or diabetic complications or for the prevention of graft rejection following transplant surgery.