18493-82-8

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-(phenylmethyl)-
• CAS NO: 18493-82-8
• Molecular Formula: C11H9ClN2O2
• Molecular Weight: 236.658
• Mol File: 18493-82-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-(phenylmethyl)-(18493-82-8)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-(phenylmethyl)-(18493-82-8)

Safety Data

• Hazardous Substances Data: 18493-82-8(Hazardous Substances Data)

Upstream product

• 5909-45-5 5-benzylpyrimidine-2,4,6-trione 
• 860760-69-6 5-benzyl-4-chloro-2,6-dimethoxypyrimidine 

Downstream Products

• 874962-11-5 C₂₂H₂₂ClN₃O₂ 
• 1400902-26-2 5-benzyl-6-(4-phenylcyclohex-1-enyl)-1H-pyrimidine-2,4-dione 
• 1400901-95-2 (E)-5-benzyl-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione 
• 1400902-32-0 (Z)-5-benzyl-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione 

Relevant articles and documents

Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators

A virtual screening approach comprising a 3-D similarity search based on known GR modulators was used to identify a novel series of non-steroidal glucocorticoid receptor (GR) antagonists. Optimization of the initial hit to provide potent compounds which e

Modified pyrimidine glucocorticoid receptor modulators

The present invention provides a novel class of modified pyrimidine compounds and compositions and methods of using the compounds as glucocorticoid receptor modulators.