18494-52-5

Basic information

• Product Name: 1-Piperidino-1-pentanone
• Synonyms: 1-Piperidino-1-pentanone
• CAS NO: 18494-52-5
• Molecular Formula: C₁₀H₁₉NO
• Molecular Weight: 169.264
• Mol File: 18494-52-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 282.5°Cat760mmHg
• Flash Point: 118°C
• Appearance: /
• Density: 0.949g/cm³
• Vapor Pressure: 0.00335mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: 1-Piperidino-1-pentanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidino-1-pentanone(18494-52-5)
• EPA Substance Registry System: 1-Piperidino-1-pentanone(18494-52-5)

Safety Data

• Hazardous Substances Data: 18494-52-5(Hazardous Substances Data)

Usage

Classification

Synthetic drug and designer drug

Chemical Class

Cathinone

Structural Relations

MDPV (Methylenedioxypyrovalerone) and α-PVP (Alpha-Pyrrolidinovalerophenone)

Psychoactive Effects

Increased energy, euphoria, and heightened alertness

Availability

Often sold as a research chemical or substitute for other stimulants like MDMA (Ecstasy) or amphetamines

Legal Status

Controlled substance in many countries

Regulation Purpose

To prevent misuse and health risks associated with consumption

Use and Distribution

Regulated due to potential for abuse and harmful effects

InChI:InChI=1/C10H19NO/c1-2-3-7-10(12)11-8-5-4-6-9-11/h2-9H2,1H3

Upstream product

• 110-89-4 piperidine 
• 2173-56-0 n-pentyl n-pentanoate 
• 638-29-9 n-valeryl chloride 
• 71-41-0 pentan-1-ol 
• 110-59-8 pentanonitrile 
• 110-62-3 pentanal 
• 109-52-4 valeric acid 
• 4426-47-5 butylboronic acid 
• 201230-82-2 carbon monoxide 
• 135676-71-0 1,5-Dipentanoyl-[1,3,5]triazinane-2,4-dione 

Downstream Products

• 49845-25-2 1-(pent-1-en-1-yl)piperidine 
• 1374639-81-2 2-butyl-3-benzoylimidazo[1,2-a]pyridine 

Relevant articles and documents

IrIII-Catalyzed direct syntheses of amides and esters using nitriles as acid equivalents: A photochemical pathway

An unprecedented IrIII[df(CF3)ppy]2(dtbbpy)PF6-catalyzed simple photochemical process for direct addition of amines and alcohols to the relatively less reactive nitrile triple bond is described herein. Various amides and esters are synthesized as the reaction products, with nitriles being the acid equivalents. A mini-library of different types of amides and esters is made using this mild and efficient process, which uses only 1 mol% of photocatalyst under visible light irradiation (λ = 445 nm). The reaction strategy is also efficient for gram-scale synthesis.

Cross-Dehydrogenating Coupling of Aldehydes with Amines/R-OTBS Ethers by Visible-Light Photoredox Catalysis: Synthesis of Amides, Esters, and Ureas

A straightforward synthesis of amides, ureas, and esters is reported by visible-light cross-dehydrogenating coupling (CDC) of aldehydes (or amine carbaldehydes) and amines/R-OTBS ethers by photoredox catalysis. The reaction is found to be general and high yielding. A plausible mechanistic pathway has been proposed for these transformations and is supported by appropriate controlled experiments.

MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS

The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2) C-C coupling in Michael addition reaction using nitriles as Michael donors; (3) dehydrogenative coupling of alcohols to give esters and hydrogen gas (4) hydrogenation of esters to form alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di- lactones), or polyesters); (5) hydrogenation of amides (including cyclic dipeptides, lactams, diamide, polypeptides and polyamides) to alcohols and amines (or diamine); (6) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (7) dehydrogenation of secondary alcohols to ketones; (8) amidation of esters (i.e., synthesis of amides from esters and amines); (9) acylation of alcohols using esters; (10) coupling of alcohols with water and a base to form carboxylic acids; and (11) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. (12) preparation of amides (including formamides, cyclic dipeptides, diamide, lactams, polypeptides and polyamides) by dehydrogenative coupling of alcohols and amines; (13) preparation of imides from diols.