184964-75-8

Upstream product

• 26291-75-8 (R)-1-((3aR,5S,6R,6aR)-2,2,6-trimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol 
• 100-39-0 benzyl bromide 
• 114144-67-1 6-O-benzyl-3-deoxy-1,2-O-isopropylidene-3-C-methyl-α-D-allofuranose 
• 184964-71-4 (1R,3S,4R,5R)-3-[(E/Z)-1-benzyloxymethyl-2-ethoxycarbonylethenyl]-4-methyl-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]octane 
• 114144-68-2 2-Benzyloxy-1-((3aR,5S,6S,6aR)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethanone 
• 545-06-2 trichloroacetonitrile 
• 184964-73-6 (1R,3S,4R,5R)-3-[(E/Z)-1-benzyloxymethyl-3-hydroxy-1-propenyl]-4-methyl-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]octane 

Downstream Products

• 145451-97-4 (3R,4S,5R,1'S)-4-hydroxy-5-(1'-hydroxy-2'-methylpropyl)-3-methylpyrrolidin-2-one-5-carboxylic acid 
• 133343-34-7 Lactacystin 
• 166541-05-5 (3R,4S,5R)-5-benzyloxymethyl-4-hydroxy-3-methyl-5-vinyl-2-pyrrolidinone 
• 199734-91-3 (3R,4S,5R)-5-benzyloxymethyl-4-(tert-butyldimethylsilyl)oxy-3-methyl-5-vinyl-2-pyrrolidinone 
• 184964-82-7 Formic acid (2R,3S,4R)-2-benzyloxymethyl-5-hydroxy-4-methyl-1-(2,2,2-trichloro-acetyl)-2-vinyl-pyrrolidin-3-yl ester 
• 184964-77-0 (1R,3S,4R,5R)-3-[(1RS)-1-benzyloxymethyl-1-trichloroacetylamino-2-propenyl]-4-methyl-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]octane 

Relevant academic research and scientific papers

Stereoselective total synthesis of (+)-lactacystin from D-glucose

The chiral and stereoselective synthesis of (+)-lactacystin 1, the first non-protein neurotrophic factor having an α,α-disubstituted α- amino acid structure, is described. The highly functionalized γ- lactam portion possessing a tetra-substituted carbon w

Total Synthesis of (+)-Lactacystin from D-Glucose

The chiral and stereoselective synthesis of (+)-lactacystin 1, the first non-protein neurotrophic factor, is described; the γ-lactam portion possessing a quaternary carbon in 1 was constructed stereoselectively from D-glucose using the allylic trichloroac