185-73-9

Basic information

• Product Name: 1-Oxa-6-thiaspiro[2.5]octane
• Synonyms: 1-Oxa-6-thiaspiro[2.5]octane
• CAS NO: 185-73-9
• Molecular Formula: C₆H₁₀OS
• Molecular Weight: 130.21
• Mol File: 185-73-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Oxa-6-thiaspiro[2.5]octane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Oxa-6-thiaspiro[2.5]octane(185-73-9)
• EPA Substance Registry System: 1-Oxa-6-thiaspiro[2.5]octane(185-73-9)

Safety Data

• Hazardous Substances Data: 185-73-9(Hazardous Substances Data)

Usage

General Description

1-Oxa-6-thiaspiro[2.5]octane is a chemical compound with a unique and complex structure. It belongs to the class of organic compounds known as spiro compounds, which consist of two fused rings sharing a single common atom. The name "1-Oxa-6-thiaspiro[2.5]octane" indicates the presence of oxygen (Oxa) and sulfur (thia) atoms in the structure, as well as the spiro[2.5]octane framework. 1-Oxa-6-thiaspiro[2.5]octane is primarily used in research and chemical synthesis, and it may have potential applications in pharmaceuticals, agrochemicals, and materials science due to its structural properties and reactivity. 1-Oxa-6-thiaspiro[2.5]octane's unique structure and potential reactivity make it an interesting target for further study and exploration in the field of organic chemistry.

Upstream product

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Downstream Products

• 38447-82-4 4-methyltetrahydro-2H-thiopyran-4-ol 
• 1458654-36-8 1,1-dioxo-4-((4-bromo-3,5-dimethylphenoxy)methyl)tetrahydro-2H-thiopyran-4-ol 
• 1458657-35-6 2-((S)-6-((R)-7-fluoro-4-(4-((4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid 
• 1458654-34-6 methyl 2-((S)-6-((R)-7-fluoro-4-(4-((1,1-dioxo-4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetate 
• 1458657-36-7 2-((S)-6-((R)-7-fluoro-4-(4-((1,1-dioxo-4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid 
• 1373115-06-0 4-[(4-bromo-3,5-dimethylphenoxy)methyl]tetrahydro-2H-thiopyran-4-ol 
• 865136-34-1 3-{2-fluoro-4-[({4'-[(4-hydroxy-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)amino]phenyl}propanoic acid 
• 865136-31-8 ethyl 3-(2-fluoro-4-{({4'-[(4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)[(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate 
• 865136-33-0 ethyl 3-{2-fluoro-4-[({4'-[(4-hydroxy-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)amino]phenyl}propanoate 
• 865136-32-9 ethyl 3-(2-fluoro-4-{({4'-[(4-hydroxy-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)[(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate 
• 1221183-91-0 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol 

Relevant articles and documents

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NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS

The present invention relates to compounds of general formula I, (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

AMINOPHENYLPROPANOIC ACID DERIVATIVE

A compound represented by the formula (1): wherein each symbol is as defined in the specification, and a salt thereof and a prodrug thereof unexpectedly have superior GPR40 receptor agonist activity, superior in the properties as a pharmaceutical product such as stability and the like, and can be a safe and useful pharmaceutical agent as a drug for the prophylaxis or treatment of GPR40 receptor related pathology or diseases such as diabetes and the like.