185-88-6Relevant articles and documents
trans-Cyclooctenes as Chiral Ligands in Rhodium-Catalyzed Asymmetric 1,4-Additions
Nagano, Tagui,Einaru, Shunsuke,Shitamichi, Kenta,Asano, Keisuke,Matsubara, Seijiro
supporting information, p. 7131 - 7133 (2020/09/11)
trans-Cyclooctenes serve as asymmetric ligands for the rhodium-catalyzed 1,4-additions of organotin reagents to enones. We demonstrate, for the first time, that these chiral olefins can provide efficient coordination spheres for asymmetric metal catalysis. As the asymmetric environment around the reaction site is constructed by the trans-cyclooctene framework, the introduction of a substituent at the allylic position further improves enantioselectivity to 93 % ee. These findings provide new chiral framework designs for the asymmetric ligands of metal catalysts.
ALDEHYDES AND KETONES EPOXIDATION WITH TRIMETHYLSULFONIUM BROMIDE IN A SLIGHTLY HYDRATED SOLID-LIQUID MEDIUM
Bouda, H.,Borredon, M. E.,Delmas, M.,Gaset A.
, p. 503 - 514 (2007/10/02)
Trimethylsulfonium bromide used in low hydrated solid-liquid phase transfer conditions is a very efficient agent for aldehyde and ketone epoxidation.
