59123-41-0

Basic information

• Product Name: 1-METHYLCYCLOOCTANOL
• Synonyms: 1-METHYLCYCLOOCTANOL;1-methyl-cyclooctano;Cyclooctanol, 1-methyl-;1-Methylcyclooctanol1-Methylcyclooctanol
• CAS NO: 59123-41-0
• Molecular Formula: C₉H₁₈O
• Molecular Weight: 142.24
• Mol File: 59123-41-0.mol

Chemical Properties

• Boiling Point: 206.3 °C at 760 mmHg
• Flash Point: 82.3 °C
• Appearance: /
• Density: 0.904 g/cm³
• Vapor Pressure: 0.0565mmHg at 25°C
• Refractive Index: 1.46
• CAS DataBase Reference: 1-METHYLCYCLOOCTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLCYCLOOCTANOL(59123-41-0)
• EPA Substance Registry System: 1-METHYLCYCLOOCTANOL(59123-41-0)

Safety Data

• Hazardous Substances Data: 59123-41-0(Hazardous Substances Data)

Usage

Uses

Used in Flavor and Fragrance Industry:
1-METHYLCYCLOOCTANOL is used as a flavoring agent and fragrance ingredient for its unique scent and mild odor, enhancing the aroma profiles in various products such as perfumes, soaps, and household cleaners.
Used in Chemical Synthesis:
1-METHYLCYCLOOCTANOL serves as a solvent in chemical reactions, facilitating the process and improving the efficiency of certain chemical transformations.
Used as an Intermediate in Organic Synthesis:
1-METHYLCYCLOOCTANOL is utilized as an intermediate in the synthesis of other organic compounds, contributing to the creation of a variety of chemical products.
Used in Pesticide and Insect Repellent Applications:
Although with potential use, 1-METHYLCYCLOOCTANOL is considered for its possible application as a pesticide and insect repellent, due to its effects on certain pests and insects.
It is crucial to handle 1-METHYLCYCLOOCTANOL with care, as it can be harmful if ingested or inhaled, and it may cause skin and eye irritation. Proper safety measures should be taken during its use and storage.

InChI:InChI=1/C9H18O/c1-9(10)7-5-3-2-4-6-8-9/h10H,2-8H2,1H3

Upstream product

• 3618-18-6 methylenecyclooctane 
• 185-88-6 1-oxaspiro[2,7]-decane 
• 933-11-9 methylcyclooctene 
• 502-49-8 cycloactanone 
• 75-16-1 methylmagnesium bromide 
• 917-54-4 methyllithium 
• 5009-32-5 non-8-en-2-one 

Downstream Products

• 381212-42-6 1α,3β-bis(tert-butyldimethylsilyloxy)-20(S)-(1-methylcyclooctyloxycarbonylmethoxy)-9,10-secopregna-5,7,10(19),16-tetraene 
• 873055-51-7 5-Amino-4-fluoro-2-(1-methylcyclooctyl)phenol 
• 109672-79-9 Isobutyric acid 1-methyl-cyclooctyl ester 

Relevant articles and documents

Regiodivergent Hydroborative Ring Opening of Epoxides via Selective C-O Bond Activation

A magnesium-catalyzed regiodivergent C-O bond cleavage protocol is presented. Readily available magnesium catalysts achieve the selective hydroboration of a wide range of epoxides and oxetanes yielding secondary and tertiary alcohols in excellent yields and regioselectivities. Experimental mechanistic investigations and DFT calculations provide insight into the unexpected regiodivergence and explain the different mechanisms of the C-O bond activation and product formation.

Controllable Intramolecular Unactivated C(sp3)-H Amination and Oxygenation of Carbamates

Dual catalyst-controlled intramolecular unactivated C(sp3)-H amination and oxygenation of carbamates merging visible-light photocatalysis and earth-abundant transition metal catalysis have been reported. Useful amino alcohol and diol derivatives could be selectively obtained from readily available tertiary alcohol derivatives. The possible mechanisms have been proposed via a 1,5-HAT process followed by Lewis acid-controlled cyclization. The nickel and zinc catalysts inhibit the formation of oxygenation and amination products, respectively. An interesting phenomenon of chirality transfer is also observed.

SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF

The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administeri

Cycloalkyl esters of mercaptoalkanoic acids

Described are the cycloalkyl esters of mercaptoalkanoic acids defined according to the structure: STR1 wherein R1 represents hydrogen or methyl; R2 represents mono C1 -C4 alkyl substituted or unsubstituted C5 -C8 cycloalkyl; R3 represents hydrogen or methyl; and N represents 0, 1 or 2 and uses thereof in augmenting or enhancing the aroma or taste of foodstuffs.

Acid-Catalyzed Olefin-Alcohol Interconversion in the 1-Methylcyclooctyl System. Strain-Relief Acceleration of the Hydration of 1-Methyl-trans-cyclooctene

Rates of reaction with aqueous perchloric acid at 25 deg C have been measured for 1-methyl-cis-cyclooctene, 1-methyl-trans-cyclooctene, and their exo isomer, methylenecyclooctane.The only products formed to any significant extent in each of these reactions are 1-methylcyclooctanol and the cis-cycloalkene, but both the trans- and exo-olefins give these products in initially noneequilibrium proportions: / = 1.27 +/- 0.05 at equilibrium, 15.1 +/- 0.9 from the trans-olefin and 0.44 +/- 0.05 from the exo-olefin.This is taken as evidence for the existence of two conformationally different 1-methylcyclooctyl carbocationic intermediates in these reactions, an unstable crown (or twist) cation formed by protonation of the trans-olefin and a (conformationally) stable boat-chair cation formed from the other two olefins and the alcohol.The barrier for interconversion of these two cations is estimated at ΔG(excit.) = 5.3 +/- 0.6 kcal mol-1.The barrier for hydration of either cation to the alcohol is also estimated, by two different methods, at ΔG(excit.) = 3.6 +/- 0.6 kcal mol-1 or 4.3 +/- 0.3 kcal mol-1.The smallness of these barriers suggests that the reaction of tertiary aliphatic carbocations with water in aqueous solution is an essentially unactivated process.These estimates plus the rate and equilibrium constants measured here allow nearly complete free energy characterization of the 1-methylcyclooctyl system.The rates of reaction of the cis- and exo-olefin with the hydronium ion are normal, but strain relief accelerates the rate of the trans-cycloalkene by a factor of 18500.