185033-64-1

Basic information

• Product Name: Benzoic acid, 3-Methoxy-4-(phenylMethoxy)-, ethyl ester
• Synonyms: Benzoic acid, 3-Methoxy-4-(phenylMethoxy)-, ethyl ester;4-Benzyloxy-3-methoxy-benzoic acid ethyl ester
• CAS NO: 185033-64-1
• Molecular Formula: C₁₇H₁₈O₄
• Molecular Weight: 286.32242
• Mol File: 185033-64-1.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 3-Methoxy-4-(phenylMethoxy)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-Methoxy-4-(phenylMethoxy)-, ethyl ester(185033-64-1)
• EPA Substance Registry System: Benzoic acid, 3-Methoxy-4-(phenylMethoxy)-, ethyl ester(185033-64-1)

Safety Data

• Hazardous Substances Data: 185033-64-1(Hazardous Substances Data)

Upstream product

• 74-96-4 ethyl bromide 
• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 100-39-0 benzyl bromide 
• 121-33-5 vanillin 
• 617-05-0 ethyl vanillate 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 100-44-7 benzyl chloride 

Downstream Products

• 179688-01-8 7-(benzyloxy)-6-methoxyquinazolin-4(3H)-one 
• 162364-72-9 7-benzyloxy-4-chloro-6-methoxyquinazoline 
• 768350-54-5 7-(benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine hydrochloride 

Relevant articles and documents

C–H-Activation approach towards the core structure of the alkaloid γ-lycorane

With a view towards the synthesis of lycorane-like structures several N-(pivaloyloxy)benzamides were reacted with cyclohexa-1,3-diene in presence of a rhodium(III) catalyst which resulted via C–H activation in the corresponding tetrahydrophenanthridinones

SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES

A compound of Formula I is disclosed as follows: or a pharmaceutically acceptable salt, prodrug, solvate, or metabolite thereof, wherein R is hydrogen, P(═O)(OH)2, P(═O)(O(C1-C18)alkylene(C6-C20)aryl)2, P(═O)(OH)(OM), P(═O)(OM)2, P═O(O2M), S(═O)(OH)2, S(═O)(O(C1-C18)alkylene(C6-C20)aryl)2, S(═O)(OH)(OM), S(═O)(OM)2; M is a monovalent or divalent metal ion, or alkylammonium ion; W is (C6-C20)aryl, (C6-C20)heteroaryl, (C1-C18)alkyl(C6-C20)aryl, (C1-C18)alkyl(C6-C20)heteroaryl, hydroxy(C6-C20)aryl, hydroxy(C6-C20)heteroaryl, (C1-C18)alkoxy(C6-C20)aryl, (C1-C18)alkoxy(C6-C20)heteroaryl, (C1-C18)alkylenedioxy(C6-C20)aryl, (C1-C18)alkylenedioxy(C6-C20)heteroaryl, halo(C6-C20)aryl, halo(C6-C20)heteroaryl, (C1-C18)alkylamino(C6-C20)aryl, (C1-C18)alkylamino(C6-C20)heteroaryl, (C1-C18)cycloalkylamino(C6-C20)aryl, or (C1-C18)cycloalkylamino(C6-C20)heteroaryl, and their OR8 substutes; R5 is (C1-C18alkoxy, hydrogen, hydroxyl, O—(C1-C18)alkyl(C6-C20)aryl, halo or OR8, or R5 and R6 are (C1-C18)dioxy provided that R7 is hydrogen; R6 is hydroxyl, O—(C1-C18)alkyl(C6-C20)aryl, halo or ORR, (C1-C18)alkoxy, (C1-C18)alkylamino, or (C1-C18)cycloalkylamino, or R6 and R7 are (C1-C18)dioxy provided that R5 is hydrogen; R7 is hydrogen, halo or OR8, hydroxyl, or O—(C1-C18)alkyl(C6-C20)aryl; and R8 is P(═O)(OH)2, P(═O)(O(C1-C18)alkyl(C6-C20)aryl)2, P(═O)(OH)(OM), or P(═O)(OM)2, P═O(O2M).

Method of lowering body temperature with (R) - 2,3-benzodiazepines

An (R)-2,3-benzodiazepine of Formula I, substantially isolated from the corresponding (S)-enantiomer thereof, is administered to lower the body temperature of an individual.