185100-52-1Relevant academic research and scientific papers
New Approach to the Coupling if γ-Amino β-Hydroxy Acids and ν,γ-Dihydroxy Acids with α-Amino Acid Esters
Palomo, Claudio,Miranda, Jose I.,Linden, Anthony
, p. 9196 - 9201 (1996)
α,α-Dichloro β-lactones, readily obtained by a highly diastereoselective cycloaddition of dichloroketene to N-Boc-α-amino aldehydes and α-(silyloxy) aldehydes, coupled efficiently with α-amino acid esters leading, after dehalogenation with H2 over 10percent Pd on charcoal, to peptide mimics under mild reaction conditions.
