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185116-43-2

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185116-43-2 Usage

Chemical Properties

White powder

Uses

Fmoc-4-aminobenzoic acid is used in the improved rapid synthesis of oligo(benzamide) block copolymers.

Check Digit Verification of cas no

The CAS Registry Mumber 185116-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,1,1 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 185116-43:
(8*1)+(7*8)+(6*5)+(5*1)+(4*1)+(3*6)+(2*4)+(1*3)=132
132 % 10 = 2
So 185116-43-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H17NO4/c24-21(25)14-9-11-15(12-10-14)23-22(26)27-13-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-12,20H,13H2,(H,23,26)(H,24,25)

185116-43-2 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
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  • Detail
  • Alfa Aesar

  • (H52828)  4-(Fmoc-amino)benzoic acid, 97%   

  • 185116-43-2

  • 250mg

  • 426.0CNY

  • Detail
  • Alfa Aesar

  • (H52828)  4-(Fmoc-amino)benzoic acid, 97%   

  • 185116-43-2

  • 1g

  • 1279.0CNY

  • Detail
  • Alfa Aesar

  • (H52828)  4-(Fmoc-amino)benzoic acid, 97%   

  • 185116-43-2

  • 5g

  • 5116.0CNY

  • Detail
  • Aldrich

  • (47307)  Fmoc-4-Abz-OH  ≥96.0% (TLC)

  • 185116-43-2

  • 47307-1G

  • 1,386.45CNY

  • Detail

185116-43-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(9H-fluoren-9-ylmethoxycarbonylamino)benzoic acid

1.2 Other means of identification

Product number -
Other names fmoc-p-amino-benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:185116-43-2 SDS

185116-43-2Relevant articles and documents

Solid-phase synthesis of coralmycin A/epi-coralmycin A and desmethoxycoralmycin A

Hawkins, Paige M. E.,Liu, Dennis Y.,Linington, Roger G.,Payne, Richard J.

supporting information, p. 6291 - 6300 (2021/07/28)

The total synthesis of the natural product coralmycin A/epi-coralmycin A, as well as a desmethoxy analogue is described. Synthesis was achievedviaa divergent, bidirectional solid-phase strategy, including a key on-resinO-acylation,OtoNacyl shift, andO-alkylation protocol to incorporate the unusual 4-amino-2-hydroxy-3-isopropoxybenzoic acid motifs. The synthetic natural product was generated as a 1?:?1 mixture of epimers at the central β-methoxyasparagine residue and exhibited potent antibacterial activity against a panel of ten Gram-negative and seven Gram-positive organisms. The desmethoxy analogue possessed significantly more potent antimicrobial activity against this panel with minimal inhibitory concentrations (MICs) as low as 50 nM.

N-aryl sulfanilamide-N-beta-D-glucopyranose diamide compound and application thereof

-

Paragraph 0029; 0034, (2021/06/26)

The invention belongs to the technical field of medicines, and relates to a preparation method and medical application of an N1-aryl sulfanilamide-N4-beta-D-glucopyranose diamide compound. The compound is shown in a general formula (I), substituent groups are described in the specification, and the compound shown in the general formula (I) and an optical active body, a diastereoisomer and a pharmaceutically acceptable salt thereof are applied to preparation of anti-tumor drugs. Based on pharmacophore characteristics and subcellular localization of CA IX and XII, a selective CA IX and XII inhibitor is designed and synthesized, polyhydroxy high-polarity glucose is selected as a tail end, a classical pharmacophore aryl sulfanilamide fragment of a targeted CAs active center is introduced through a flexible aliphatic chain and a rigid aromatic structure, the overall structure can selectively inhibit catalytic activity of extracellular CA IX and XII, an anti-tumor effect is achieved, and therefore, the compound has a good application prospect.

Synthesis, biological evaluation, and docking studies of PAR2-AP-derived pseudopeptides as inhibitors of kallikrein 5 and 6

Severino, Beatrice,Fiorino, Ferdinando,Corvino, Angela,Caliendo, Giuseppe,Santagada, Vincenzo,Assis, Diego Magno,Oliveira, Juliana R.,Juliano, Luiz,Manganelli, Serena,Benfenati, Emilio,Frecentese, Francesco,Perissutti, Elisa,Juliano, Maria Aparecida

, p. 45 - 52 (2015/02/19)

A series of protease activated receptor 2 activating peptide (PAR2-AP) derivatives (1-15) were designed and synthesized. The obtained compounds were tested on a panel of human kallikreins (hKLK1, hKLK2, hKLK5, hKLK6, and hKLK7) and were found completely i

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