185121-89-5Relevant academic research and scientific papers
C-fucopeptides as selectin antagonists: Attachment of lipid moieties enhances the activity
Weltering, Thomas J.,Weitz-Schmidt, Gabriele,Wong, Chi-Huey
, p. 9033 - 9036 (1996)
The biological activity of a potent selectin antagonist could be 40-fold enhanced by attachment of a lipid moiety. Also an enantioselective synthesis of β,ω-dihydroxyamino acids by Sharpless asymmetric dihydroxylation (AD-reaction) allowed general access to this important class of compounds. Copyright (C) 1996 Elsevier Science Ltd.
