18528-78-4 Usage
Description
2,3-DIHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE, also known as 9-amino-tetrahydroquinoline, is a chemical compound with potential pharmaceutical applications. It belongs to the class of organic compounds known as indolines, which are cyclic compounds containing an indole moiety, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. 2,3-DIHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE has been studied for its potential use as a building block in the synthesis of various biologically active molecules and pharmaceuticals. It is also being investigated for its potential pharmacological activities, such as its anti-inflammatory and anti-cancer properties. Further research is needed to fully understand and harness the potential of this chemical.
Uses
Used in Pharmaceutical Industry:
2,3-DIHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE is used as a building block for the synthesis of biologically active molecules and pharmaceuticals due to its unique chemical structure and potential to be incorporated into various drug candidates.
Used in Anti-inflammatory Applications:
2,3-DIHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE is used as an anti-inflammatory agent for its potential to modulate inflammatory pathways and alleviate inflammation-related conditions.
Used in Anti-cancer Applications:
2,3-DIHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE is used as an anti-cancer agent for its potential to target and inhibit cancer cell growth and proliferation, as well as its ability to enhance the efficacy of conventional chemotherapeutic drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 18528-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,2 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18528-78:
(7*1)+(6*8)+(5*5)+(4*2)+(3*8)+(2*7)+(1*8)=134
134 % 10 = 4
So 18528-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H12N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-2,4,6H,3,5,7H2,(H2,13,14)
18528-78-4Relevant articles and documents
Ionization constants of the drugs amiridin and tacrine and their analogs
Goncharenko,Kaganskii,Portnov,Granik
, p. 769 - 772 (1993)
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A concise construction of polycyclic quinolines via annulation of ω-cyano-1-alkynes with diaryliodonium salts
Wang, Yong,Chen, Chao,Zhang, Shu,Lou, Zhenbang,Su, Xiang,Wen, Lirong,Li, Ming
supporting information, p. 4794 - 4797 (2013/10/08)
A concise construction of polycyclic quinolines via intramolecular [2 + 2 + 2] annulation of ω-cyano-1-alkynes with diaryliodonium salts was realized. The process produced polycyclic quinolines in high yields with readily available staring materials and was tolerated with halogen substituents.
Sulfuric acid-modified PEG-6000 (PEG-OSO3H): An efficient, bio-degradable and reusable polymeric catalyst for the solvent-free synthesis of poly-substituted quinolines under microwave irradiation
Hasaninejad, Alireza,Zare, Abdolkarim,Shekouhy, Mohsen,Ameri-Rad, Javad
experimental part, p. 958 - 964 (2011/05/12)
Sulfuric acid-modified polyethylene glycol 6000 (PEG-OSO3H) is applied as an efficient and eco-friendly polymeric catalyst for Friedlaender synthesis of poly-substituted quinolines from 2-aminoaryl ketones (or anthranilonitrile) and carbonyl compounds possessing a reactive methylene group under microwave irradiation and solvent-free conditions. The reactions are completed in short times, and the products are obtained in good to excellent yields. The Royal Society of Chemistry.