18529-17-4 Usage
Description
ETHYL 3-(4-FLUOROANILINO)CROTONATE is an organic compound characterized by the chemical formula C13H13NO3F. It is a derivative of crotonic acid, featuring a fluorine-substituted aniline group. ETHYL 3-(4-FLUOROANILINO)CROTONATE is recognized for its potential as a precursor in the synthesis of pharmaceuticals and agrochemicals, with applications in developing drugs for a range of therapeutic uses, such as anti-inflammatory and analgesic effects. Its distinctive chemical structure also positions it as a valuable asset in organic chemistry for the synthesis of new molecules with a variety of biological activities. In essence, ETHYL 3-(4-FLUOROANILINO)CROTONATE serves as a crucial building block in the pharmaceutical and agrochemical industries for the creation of a multitude of valuable compounds.
Uses
Used in Pharmaceutical Industry:
ETHYL 3-(4-FLUOROANILINO)CROTONATE is used as a precursor in the synthesis of pharmaceuticals for its potential to develop drugs with anti-inflammatory and analgesic properties. Its unique structure allows for the creation of new molecules with diverse biological activities, contributing to the advancement of therapeutic options.
Used in Agrochemical Industry:
In the agrochemical sector, ETHYL 3-(4-FLUOROANILINO)CROTONATE is utilized as a starting material for the synthesis of agrochemicals, potentially leading to the development of new pesticides or other agricultural chemicals that can improve crop protection and yield.
Used in Organic Chemistry Research:
ETHYL 3-(4-FLUOROANILINO)CROTONATE is employed as a key intermediate in organic chemistry for the synthesis of novel compounds. Its fluorine-substituted aniline group provides a platform for exploring new chemical reactions and the generation of molecules with potential applications in various fields, including medicine, materials science, and beyond.
Check Digit Verification of cas no
The CAS Registry Mumber 18529-17-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,2 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18529-17:
(7*1)+(6*8)+(5*5)+(4*2)+(3*9)+(2*1)+(1*7)=124
124 % 10 = 4
So 18529-17-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H14FNO2/c1-3-16-12(15)8-9(2)14-11-6-4-10(13)5-7-11/h4-8,14H,3H2,1-2H3/b9-8+
18529-17-4Relevant articles and documents
Facile one-pot multicomponent synthesis of highly functionalized tetrahydropyridines using thiamine hydrochloride as an organocatalyst
Singh, Sandeep,Gupta, Annah,Kapoor, Kamal K.
, p. 1056 - 1063 (2020)
Thiamine hydrochloride (VitB1) has been found to be an efficient catalyst for the multicomponent synthesis of highly functionalized tetrahydropyridines from the reaction of β-ketoester, aromatic aldehydes and anilines. VitB1 is easily available, cheap, and eco benign.
Ecofriendly and facile Nano ZnO catalyzed solvent-free enamination of 1,3-dicarbonyls
Indulkar, Utkarsha U.,Kale, Sandip R.,Gawande, Manoj B.,Jayaram, Radha V.
supporting information; experimental part, p. 3857 - 3860 (2012/08/27)
Nano zinc oxide (Nano-ZnO) was explored as a reusable catalyst for the enamination of 1,3-dicarbonyls using diverse amines. To make the process environmentally viable, the reaction was carried out under solvent-free conditions and found to give good yield of desired products. The catalyst was characterized by various analytical techniques such as UV-spectroscopy, XRD, and TEM. The catalyst was found to be reusable up to four catalytic cycles without any appreciable loss in activity.
A facile, chemoselective and eco-friendly solid phase synthesis of enaminones catalyzed by L-Proline
Bhupathi, Raja S.,Devi, B.Rama,Dubey
experimental part, p. 5521 - 5524 (2012/07/13)
A facile and chemoselective method for the synthesis of enaminones by the reaction of aromatic primary amines with various β-ketoesters in the presence of L-proline as activator under solid phase is described. The reactions are promoted by the catalyst in short time (5-6 min) under ambient conditions, without any side products.
