185315-52-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-2-pyridineacetonitrile is used as a key intermediate for the synthesis of various pharmaceutical drugs and agrochemicals. Its applications include the production of anti-inflammatory drugs, anti-cancer agents, and other therapeutic compounds. 3-Chloro-2-pyridineacetonitrile's unique structure and properties make it a valuable building block in the development of novel and effective medications.
Used in Organic Synthesis:
3-Chloro-2-pyridineacetonitrile is utilized as a starting material in the synthesis of pyridine derivatives and heterocyclic compounds. Its reactivity and functional groups enable the formation of a wide range of chemical products, contributing to the advancement of organic chemistry and the discovery of new compounds with potential applications in various fields.
Used in Material Science:
3-Chloro-2-pyridineacetonitrile has potential applications in the field of material science, where its unique properties can be harnessed to develop new materials with specific characteristics. Its use in material synthesis can lead to the creation of innovative products with improved performance and functionality.

Upstream product

• 2402-77-9 2,3-dichloro-pyridine 
• 75-05-8 acetonitrile 

Downstream Products

• 830348-07-7 N-(2-(3-chloropyridine-2-yl)ethyl)-2-(trifluoromethyl)benzamide 
• 1092476-62-4 (R)-N'-[3,5-bis(trifluoromethyl)phenyl]-2-(3-chloro-2-pyridinyl)-2-(4-methyl-1-piperazinyl)acetohydrazide 
• 1092476-61-3 (S)-N'-[3,5-bis(trifluoromethyl)phenyl]-2-(3-chloro-2-pyridinyl)-2-(4-methyl-1-piperazinyl)acetohydrazide 
• 885167-73-7 2-(3-chloropyridin-2-yl)acetic acid 
• 1092477-86-5 methyl (3-chloro-2-pyridinyl)acetate 
• 1092477-85-4 (3-chloro-2-pyridinyl)acetic acid hydrochloride 

Relevant academic research and scientific papers

UREA DERIVATIVES AND USES THEREOF

The present invention provides novel compounds of any one of Formulae (I)-(III), and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I)-(III) and pharmaceutical compositions thereof that are mucus penetrating. The invention also provides methods and kits for using the inventive compounds, and pharmaceutical compositions thereof, for treating and/or preventing diseases associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor (e.g., vascular endothelial growth factor (VEGF)), such as proliferative diseases (e.g., cancers, benign neoplasms, inflammatory diseases, autoimmune diseases) and ocular diseases (e.g., macular degeneration, glaucoma, diabetic retinopathy, retinoblastoma, edema, uveitis, dry eye, blepharitis, and post-surgical inflammation) in a subject in need thereof.

N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR

The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein: each R1 is independently selected from the group consisting of Cl, Br, CH3 and CF3; X is carbon or nitrogen; R1a is H or a straight C1-3 alkyl group; R2a is H or a methyl group R2 is selected from the group consisting of C1-3alkyl, H and -(CH2)n-, wherein n is 3 or 4 and the terminal carbon of the chain is bonded to the carbon atom adjacent to the nitrogen bearing the R2 group, such that a fused 6,5 or 6,6-bicyclic ring is formed. Y is selected from the group consisting of: phenyl which may be unsubstituted or substituted by one or more substituents independently selected from the group consisting of C1-3alkyl, C1-3alkoxy, halogen, C1-3alkyl substituted by 1 to 7 fluoro atoms and C1-3alkoxy substituted by 1 to 7 fluoro atoms; pyridyl which may be unsubstituted or substituted by one or more substituents independently selected from the group consisting of C1-3alkyl, OCH3, CF3, CN, and halogen; naphthyl which may be unsubstituted or substituted by one or more substituents independently selected from the group consisting of F and OCH3; pyrimidinyl; imidazo[1,2-a]pyridine-6-yl; benzothiophen-2-yl; benzothiophen-5-yl; benzofuran-2-yl; dibenzo[b,d]furan-3-yl; dibenzo[b,d]thiophen-2-yl; dibenzo[b,d]thiophen-4-yl; 1,3- benzodioxol-5-yl; 2,3-dihydro-1,4-benzodioxin-5-yl; 2,3-dihydro-1,4-benzodioxin-6-yl; 2,3- dihydro-1-benzofuran-4-yl; 2,2-difluoro-1,3-benzodiox-4-yl; pyridazinyl; imidazolyl; oxazolyl; pyrazolyl; thiazolyl; and triazolyl; with the proviso that when Y is 2,3-dihydro-1,4-benzodioxin-6-yl, R1 is not Cl; processes for their preparation, intermediates useble in these processes, pharmaceutical compositions containing them and their use in therapy, for example as modulators of of the growth hormone secretagogue receptor (also referred to as the ghrelin receptor or GHSR1a receptor) and/or for the treatment and/or prophylaxis of a disorder mediated by the ghrelin receptor.

N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides

Compound of general formula (I): Process for preparing this compound. Fungicidal composition comprising a compound of general formula (I). Method for treating plants by applying a compound of general formula (I) or a composition comprising it.