185316-16-9

Basic information

• Product Name: 4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylethynyl)-benzoic acid ethyl ester
• Synonyms: 4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylethynyl)-benzoic acid ethyl ester
• CAS NO: 185316-16-9
• Molecular Weight: 389.494
• Mol File: 185316-16-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylethynyl)-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylethynyl)-benzoic acid ethyl ester(185316-16-9)
• EPA Substance Registry System: 4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylethynyl)-benzoic acid ethyl ester(185316-16-9)

Safety Data

• Hazardous Substances Data: 185316-16-9(Hazardous Substances Data)

Upstream product

• 135631-90-2 4,4-dimethyl-6-bromo-2-oxo-1,2,3,4-tetrahydroquinoline 
• 185316-41-0 4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-6[(trimethylsilyl)ethynyl]quinoline 
• 185316-42-1 4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-6-ethynylquinoline 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 75-30-9 2-iodo-propane 
• 185316-43-2 ethyl 4-[(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-6-quinolinyl)ethynyl]benzoate 

Relevant articles and documents

Synthesis and biological activity of 1,2,3,4-tetrahydroquinoline and 3,4-(1H)-dihydroquinolin-2-one analogs of retinoic acid

Retinoids are natural and synthetic analogs of the hormone retinoic acid. Retinoids are currently being investigated clinically as drugs in several areas, including dermatology and oncology. We report the synthesis and biological activity of a new series of potent, RAR-specific retinoids substituted with a 1,2,3,4-tetrahydroquinoline or a 3,4-1H)-dihydroquinolin-2-one group.