185318-74-5

Usage

Uses

Used in Pharmaceutical Industry:
AnthranceA is used as an anticancer agent for its strong cytotoxic effects against various cancer cell lines, including breast, lung, and colon cancer cells. It induces apoptosis and inhibits cell proliferation, demonstrating promising antitumor activity in animal models.
Used in Cancer Treatment Research:
AnthranceA is used as a potential candidate for the development of novel therapies for cancer treatment due to its well-tolerated nature and relatively low toxicity. Its mechanism of action, which involves the generation of reactive oxygen species and the disruption of cellular redox balance, leads to the selective killing of cancer cells, making it a promising compound for further research and development in cancer treatment.

Upstream product

• 185318-75-6 4,5,6,7-tetrafluorofluorescein diacetate 
• 652-12-0 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione 
• 108-46-3 recorcinol 

Relevant academic research and scientific papers

Online monitoring of microwave-enhanced reactions by UV/Vis spectroscopy

Microwave-enhanced reactions are very fast in comparison to thermal reactions. They are often finished within a few minutes. Thus, the determination of the end point often fails, because conventional analytical methods are too slow. We developed a fast method using a UV/Vis sensor, which allows a direct online monitoring of the reaction process. The potency of the method is demonstrated by means of five representative reactions.

One-pot synthesis of tetrafluoro- and tetrachlorofluorescein derivatives and their stabilization by β-cyclodextrin

A highly efficient one-pot procedure for the preparation of fluorescein-based dyes with relatively high yield was investigated. Significantly, introduction of these fluoro and chloro functional groups and forming host-guest complexes with cyclodextrins partially enhanced the photostability of these dyes. A highly efficient one-pot synthesis of fluorescein-based halogenated dyes with relatively high yield was reported. Introduction of fluoro and chloro functional groups and forming host-guest complexes with cyclodextrins enhanced their photostability. Copyright

Ring-fluorinated fluoresceins as an organic photosensitizer for dye-sensitized solar cells using nanocrystalline zinc oxide

Four kinds of ring-fluorinated fluoresceins and sulfofluorescein from tetrafluororesorcinol and/or tetrafluorophthalic anhydride have been synthesized and the photochemical properties of the zinc oxide nanocrystalline electrode sensitized by the ring-fluorinated fluoresceins were investigated.

Fluorinated xanthene derivatives

The family of dyes of the invention are fluoresceins and rhodols that are directly substituted on one or more aromatic carbons by fluorine. These fluorine-substituted fluorescent dyes possess greater photostability and have lower sensitivity to pH changes in the physiological range of 6-8 than do non-fluorinated dyes, exhibit less quenching when conjugated to a substance, and possess additional advantages. The dyes of the invention are useful as detectable tracers and for preparing conjugates of organic and inorganic substances.