185329-66-2

Upstream product

• 16878-42-5 4-amino-2,6-diphenyl-7(8H)-pteridinone 
• 21740-23-8 3,5-O-bis(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride 

Downstream Products

• 195442-59-2 4-Amino-8-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2,6-diphenyl-8H-pteridin-7-one 
• 195442-54-7 4-Amino-8-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2,6-diphenyl-8H-pteridin-7-one 

Relevant academic research and scientific papers

A new efficient method in nucleoside synthesis

A new stereo- and regioselective synthesis for adenosine analogous nucleosides is described. Starting from 2- and 6-substituted 4-amino-7(8H)-pteridinones, DBU deprotonation and the ribosylation with an α-haloribofuranose derivative leads to the corresponding pteridine-N-8-β-D-nucleosides in reasonably good yields.