185376-75-4

Basic information

• Product Name: (R)-3-(benzylamino)-1-phenylpropan-1-ol
• Synonyms: (R)-3-(benzylamino)-1-phenylpropan-1-ol
• CAS NO: 185376-75-4
• Molecular Weight: 241.333
• Mol File: 185376-75-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-(benzylamino)-1-phenylpropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(benzylamino)-1-phenylpropan-1-ol(185376-75-4)
• EPA Substance Registry System: (R)-3-(benzylamino)-1-phenylpropan-1-ol(185376-75-4)

Safety Data

• Hazardous Substances Data: 185376-75-4(Hazardous Substances Data)

Upstream product

• 27152-63-2 3-(N-Benzylamino)-1-phenylpropan-1-on 
• 100306-33-0 (1R)-3-chloro-1-phenylpropanol 
• 100-46-9 benzylamine 

Downstream Products

• 138750-31-9 (1R)-3-amino-1-phenyl-1-propanol 
• 1316850-19-7 4-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine 
• 1316850-18-6 (R)-3-(benzo[d]thiazol-2-ylamino)-1-phenylpropan-1-ol 
• 185376-71-0 2-[Benzyl-((R)-3-hydroxy-3-phenyl-propyl)-amino]-1-phenyl-ethanone 
• 215391-90-5 3-[Benzyl-((R)-3-hydroxy-3-phenyl-propyl)-amino]-1-phenyl-propan-1-one 

Relevant articles and documents

Asymmetric Hydrogenation of β-Secondary Amino Ketones Catalyzed by a Ruthenocenyl Phosphino-oxazoline-ruthenium Complex (RuPHOX-Ru): The Synthesis of γ-Secondary Amino Alcohols

A ruthenocenyl phosphino-oxazoline-ruthenium complex (RuPHOX-Ru) was applied successfully to the asymmetric hydrogenation of β-secondary amino ketones, directly affording the corresponding chiral γ-secondary amino alcohols in up to 99% yield and with 99% ee. Reaction with β-(benzylamino)-1-phenylpropan-1-one could be performed on a gram-scale with a relatively low catalyst loading (up to 2000 S/C). The resulting hydrogenated product could be used for the synthesis of synthetically useful compounds.