138750-31-9

Basic information

• Product Name: (R)-3-AMINO-1-PHENYL-PROPAN-1-OL
• Synonyms: (R)-3-AMINO-1-PHENYL-PROPAN-1-OL
• CAS NO: 138750-31-9
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• Mol File: 138750-31-9.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3-AMINO-1-PHENYL-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-AMINO-1-PHENYL-PROPAN-1-OL(138750-31-9)
• EPA Substance Registry System: (R)-3-AMINO-1-PHENYL-PROPAN-1-OL(138750-31-9)

Safety Data

• Hazardous Substances Data: 138750-31-9(Hazardous Substances Data)

Usage

General Description

"(R)-3-AMINO-1-PHENYL-PROPAN-1-OL" is a chemical compound with the molecular formula C9H13NO. It is classified as an amino alcohol, containing a phenyl group and an amino group attached to a propan-1-ol backbone. (R)-3-AMINO-1-PHENYL-PROPAN-1-OL is a chiral molecule, meaning it has a non-superimposable mirror image, and the (R)-stereoisomer is its most stable form. (R)-3-AMINO-1-PHENYL-PROPAN-1-OL may have potential applications in organic synthesis, pharmaceutical research, and biochemical studies due to its unique structure and properties. Further research and testing are needed to fully understand its potential uses and effects.

Upstream product

• 73627-97-1 3-hydroxy-3-phenylpropanenitrile 
• 73627-97-1 (R)-3-phenyl-3-hydroxypropanenitrile 
• 185376-75-4 (R)-3-(benzylamino)-1-phenylpropan-1-ol 
• 27152-63-2 3-(N-Benzylamino)-1-phenylpropan-1-on 
• 7781-98-8 ethyl-3-hydroxybenzoate 
• 836684-63-0 3-(3-(benzyloxy)phenyl)-3-oxopropanenitrile 
• 63888-94-8 ethyl 3-(benzyloxy)benzoate 
• 115290-78-3 (1R) 3-phenyl-3-hydroxypropyl methanesulfonate 
• 96-09-3 styrene oxide 
• 127073-84-1 (R)-3-iodo-1-phenyl-1-propanol 
• 100306-33-0 (1R)-3-chloro-1-phenylpropanol 
• 100-42-5 styrene 
• 614-16-4 Benzoylacetonitrile 
• 40435-14-1 (S)-1-phenyl-2-(tosyloxy)ethanol 

Downstream Products

• 130194-43-3 (R)-Norfluoxetine 
• 1316850-19-7 4-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine 
• 1316850-18-6 (R)-3-(benzo[d]thiazol-2-ylamino)-1-phenylpropan-1-ol 
• 82857-40-7 rac-tomoxetine hydrochloride 
• 82248-59-7 atomoxetine hydrochloride 
• 191733-30-9 (S)-N-(ethoxycarbonyl)-3-(4-(trifluoromethyl)phenoxy)-3-phenyl-1-propanamine 
• 191733-29-6 (S)-N-(ethoxycarbonyl)-3-(2-methoxyphenoxy)-3-phenyl-1-propanamine 
• 191733-28-5 (S)-N-(ethoxycarbonyl)-3-(2-methylphenoxy)-3-phenyl-1-propanamine 
• 112066-66-7 (S)-N-methyl-3-(2-methoxyphenoxy)-3-phenyl-1-propanamine 
• 105314-53-2 (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine 
• 100568-02-3 (S)-fluoxetine 
• 114247-09-5 (R)-fluoxetine hydrochloride 
• 115290-81-8 (R)-N-methyl-3-phenyl-3-hydroxypropylamine 
• 54910-89-3 (R)-fluoxetine 

Relevant articles and documents

Asymmetric Hydrogenation of β-Secondary Amino Ketones Catalyzed by a Ruthenocenyl Phosphino-oxazoline-ruthenium Complex (RuPHOX-Ru): The Synthesis of γ-Secondary Amino Alcohols

A ruthenocenyl phosphino-oxazoline-ruthenium complex (RuPHOX-Ru) was applied successfully to the asymmetric hydrogenation of β-secondary amino ketones, directly affording the corresponding chiral γ-secondary amino alcohols in up to 99% yield and with 99% ee. Reaction with β-(benzylamino)-1-phenylpropan-1-one could be performed on a gram-scale with a relatively low catalyst loading (up to 2000 S/C). The resulting hydrogenated product could be used for the synthesis of synthetically useful compounds.

Synthesis and catalytic properties of 4-aryl-2,3-dihydro-4 H -pyrimido[2,3- b ]benzothiazoles for asymmetric acyl or carboxyl group transfer reactions

4-Aryl-2,3-dihydro-4H-pyrimido[2,3-b]benzothiazoles (4-Ar-DHPBs) were synthesized and their catalytic activity and selectivity in kinetic resolution of a secondary alcohol as well as in the Steglich rearrangement and related reactions were evaluated. 4-Aryl-DHPBs showed low enantioselectivity in the acylative kinetic resolution of 1-phenylethanol. Conversely, they catalyzed the Steglich rearrangement with moderate to excellent enantioselectivity, demonstrating the possibility for remote stereocontrol by introduction of a substituent at the 4-position of DHPB.

ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS

Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.