185383-68-0Relevant articles and documents
3-[[(4-aryl-1-piperazinyl)alkyl]cyclohexyl]-1H-indoles as dopamine D2 partial agonists and autoreceptor agonists
Wustrow, David J.,Smith III, William J.,Corbin, Ann E.,Davis, M. Duff,Georgic, Lynn M.,Pugsley, Thomas A.,Whetzel, Steven Z.,Heffner, Thomas G.,Wise, Lawrence D.
, p. 250 - 259 (2007/10/03)
A series of arylpiperazines and tetrahydropyridines joined to indoles by semirigid cycloalkyl spacers were prepared. Target compounds were studied for their ability to bind to the DA D2 receptor in vitro and to inhibit dopamine synthesis and spontaneous l