185390-53-8

Basic information

• Product Name: Acetic acid, phenoxy-, 4-cyanophenyl ester
• CAS NO: 185390-53-8
• Molecular Formula: C15H11NO3
• Mol File: 185390-53-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, phenoxy-, 4-cyanophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, phenoxy-, 4-cyanophenyl ester(185390-53-8)
• EPA Substance Registry System: Acetic acid, phenoxy-, 4-cyanophenyl ester(185390-53-8)

Safety Data

• Hazardous Substances Data: 185390-53-8(Hazardous Substances Data)

Upstream product

• 767-00-0 4-cyanophenol 
• 701-99-5 Phenoxyacetyl chloride 

Downstream Products

• 18861-15-9 N-benzyl-2-phenoxyacetamide 
• 18861-22-8 N-(4-Chloro-benzyl)-2-phenoxy-acetamide 

Relevant articles and documents

Kinetics of Aminolysis of Phenyl Phenoxyacetates with Benzylamines in Acetonitrile

Kinetic studies are carried out on the reactions of benzylamines with phenyl phenoxyacetates in acetonitrile.Based on (i) the large magnitude of various selectivity parameters, ρx, ρz and ρxz, (ii) the normal kinetic isotope effects (kH/kD > 1.0) involving deuterated benzylamine nucleophiles and (iii) the low entalpies and entropies of activation, it was cocncluded that the reactions proceed by a stepwise mechanism with rate-limiting breakdown of the tetrahedral zwitterionic intermadiate.There are, however, two pathways in the rate-limiting breakdown step of the intermediate, the uncatalysed and base-catalysed.The latter path is characterized by the larger ρxz and kH/kD values, and lower activation parameters than those the uncatalyzed path.