185390-65-2Relevant academic research and scientific papers
Synthesis and alkylation of 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(1H)thione
Dyachenko,Krivokolysko,Litvinov
, p. 1055 - 1057 (1996)
By condensation of the anilide of acetoacetic acid, propionaldehyde, and cyanothioacetamide, 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(1H)thione has been obtained. In an alkaline medium, this compound is alkylated, forming the corresponding substituted 2-pyridyl sulfides, From these pyridines, substituted thieno[2,3-b]pyridines have been synthesized through the Thorpe-Ziegler reaction. 1997 Plenum Publishing Corporation.
