Chemistry of Heterocyclic Compounds p. 1055 - 1057 (1996)
Update date:2022-08-04
Topics:
Dyachenko
Krivokolysko
Litvinov
By condensation of the anilide of acetoacetic acid, propionaldehyde, and cyanothioacetamide, 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(1H)thione has been obtained. In an alkaline medium, this compound is alkylated, forming the corresponding substituted 2-pyridyl sulfides, From these pyridines, substituted thieno[2,3-b]pyridines have been synthesized through the Thorpe-Ziegler reaction. 1997 Plenum Publishing Corporation.
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Doi:10.1039/CC9960002657
(1996)Doi:10.1021/acs.jmedchem.5b01780
(2016)Doi:10.1002/jlac.199619961226
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(1997)Doi:10.1021/ac049919h
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