185408-19-9Relevant academic research and scientific papers
Synthesis of a hybrid analog of the esperamicin and dynemicin cores
Mastalerz, Harold,Doyle, Terrence W.,Kadow, John F.,Vyas, Dolatrai M.
, p. 8687 - 8690 (1996)
An enediyne analog (2, R=H) that is a hybrid of the core structures of esperamicin and dynemicin was prepared. The key step in its synthesis was a Reissert-type reaction that involved intramolecular addition of the anion of a Z-1,3-diyn-2-ene to an N-acyl
