185447-96-5Relevant academic research and scientific papers
Nicotinoyl azide (NCA)-mediated Mitsunobu reaction: An expedient one-pot transformation of alcohols into azides
Papeo, Gianluca,Posteri, Helena,Vianello, Paola,Varasi, Mario
, p. 2886 - 2892 (2007/10/03)
A practical and simple method that allows preparation of azides from alcohols is described. The process involves oxyphosphonium-type activation and it is based upon the use of nicotinoyl azide (NCA), a cheap and easily accessible azide ion source.
Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors
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, (2008/06/13)
The invention relates to a novel drug combination therapy useful in the treatment of dementia comprising administering an 1-aminocyclohexane derivative such as memantine or neramexane and an acetylcholinesterase inhibitor (AChEI) such as galantamine, tacrine, donepezil, or rivastigmine.
Unsaturated 1-Amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists
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, (2008/06/13)
Unsaturated 1-Amino-alkylcyclohexane compounds which are systemically-active as NMDA, 5HT3, and nicotinic receptor antagonists, pharmaceutical compositions comprising the same, method of preparation thereof, and method of treating CNS disorders which involve disturbances of glutamatergic, serotoninergic, and nicotinic transmission, treating immunomodulatory disorders, and antimalaria, antitrypanosomal, anti-Borna virus, anti-HSV and anti-Hepatitis C virus activity.
Magnesium trifluoromethanesulfonimide(triflimide) promoted substitution reactions of allylic and benzylic acetates. Magnesium triflimide as a substitute for magnesium perchlorate.
Grieco, Paul A.,Handy, Scott T.
, p. 2645 - 2648 (2007/10/03)
Magnesium triflimide(10 mol% in methylene chloride) is a convenient catalyst for the nucleophilic substitution of allylic and benzylic acetates, and constitutes a useful alternative to magnesium perchlorate.
Lithium cobalt-bis-dicarbollide catalyzed substitution reactions of allylic acetates
Grieco, Paul A.,DuBay, William J.,Todd, Lee J.
, p. 8707 - 8710 (2007/10/03)
Lithium cobalt-bis-dicarbollide (1), in which the lithium is weakly coordinated to the Co(B9C2H11)2-1 anion, is an effective catalyst for the substitution of allylic acetates by a variety of nucleophiles.
