18554-50-2Relevant academic research and scientific papers
Synthesis of substituted fluorenes by cascade allenylation, electrocyclization and intramolecular friedel-crafts reaction of 1,3-diene-substituted propargylic alcohols
Xu, Xiangsheng,Li, Tao,Li, Xiaoqing,Shao, Jiangbin
supporting information, p. 383 - 388 (2013/04/23)
A concise, one-step synthesis of substituted fluorenes through TiCl 4-promoted cascade allenylation, electrocyclization and intramolecular Friedel-Crafts reaction of 1,3-diene-substituted propargylic alcohols has been developed. An interesting substituent-dependent regioselectivity was observed.
Highly efficient synthesis of polysubstituted fluorene via iron-catalyzed intramolecular Friedel-Crafts alkylation of biaryl alcohols
Sarkar, Soumen,Maiti, Sukhendu,Bera, Krishnendu,Jalal, Swapnadeep,Jana, Umasish
, p. 5544 - 5547 (2012/11/07)
An efficient and mild Fe(III)-catalyzed intramolecular Friedel-Crafts alkylation of biaryl methanol derivatives has been developed to achieve the substituted fluorene derivatives. The present reaction provides an excellent alternative to published methods
