185559-52-8

Basic information

• Product Name: CarbaMic acid, [3-(phenylMethyl)-3-azabicyclo[3.1.0]hex-6-yl]-, 1,1-diMethylethyl ester, [1R-(1a,5a,6a)]-
• Synonyms: CarbaMic acid, [3-(phenylMethyl)-3-azabicyclo[3.1.0]hex-6-yl]-, 1,1-diMethylethyl ester, [1R-(1a,5a,6a)]-
• CAS NO: 185559-52-8
• Molecular Formula: C₁₇H₂₄N₂O₂
• Molecular Weight: 288.38466
• Mol File: 185559-52-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CarbaMic acid, [3-(phenylMethyl)-3-azabicyclo[3.1.0]hex-6-yl]-, 1,1-diMethylethyl ester, [1R-(1a,5a,6a)]-(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMic acid, [3-(phenylMethyl)-3-azabicyclo[3.1.0]hex-6-yl]-, 1,1-diMethylethyl ester, [1R-(1a,5a,6a)]-(185559-52-8)
• EPA Substance Registry System: CarbaMic acid, [3-(phenylMethyl)-3-azabicyclo[3.1.0]hex-6-yl]-, 1,1-diMethylethyl ester, [1R-(1a,5a,6a)]-(185559-52-8)

Safety Data

• Hazardous Substances Data: 185559-52-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 151860-17-2 (1α,5α,6α)-3-N-benzyl-6-amino-3-aza-bicyclo[3.1.0]hexane 
• 151860-15-0 (1α,5α,6α)-3-N-benzyl-6-nitro-2,4-dioxo-3-azabicyclo[3.1.0]hexane 
• 151860-16-1 (1α,5α,6α)-3-N-benzyl-6-nitro-3-azabicyclo[3.1.0]hexane 
• 1631-26-1 1-benzyl-1H-pyrrole-2,5-dione 

Downstream Products

• 1206908-58-8 ethyl 3-[(1R,5S,6s)-6-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-azabicyclo[3.1.0]hex-3-yl]benzoate 
• 1206907-94-9 di-tert-butyl[(1R,5S,6s)-3-benzyl-3-azabicyclo[3.1.0]hex-6-yl]imidodicarbonate 
• 134575-66-9 7-([1α,5α,6α]-6-tert-Butoxycarbonylamino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid,ethyl ester 
• 256369-34-3 (1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane ditosylate salt 
• 146836-84-2 trovafloxacin mesylate 
• 134575-17-0 tert-butyl (1R,5S,6R)-3-azabicyclo[3.1.0]hexan-6-ylcarbamate 

Relevant articles and documents

Synthesis of azabicyclo[3.1.0]amine analogues of anacardic acid as potent antibacterial agents

Azabicyclo[3.1.0]amine analogues of anacardic acid (16a, 16b, 18a, 18b, 19 and 19b) were synthesized from anacardic acid and tested for their antibacterial activity against Gram positive and Gram negative bacteria. Most of the compounds are having potency at par with ampicillin and inferior with other standard drugs.

Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors

The induction of conformationally restricted N-(aryl or heteroaryl)-3-azabicyclo[3.1.0]hexane derivatives at P2 region of compounds of 2-cyanopyrrolidine class was explored to develop novel DPP-IV inhibitors. The synthesis, structure-activity r

AZABICYCLIC MUSCARINIC RECEPTOR ANTAGONISTS

The present invention generally relates to muscarinic receptor antagonists, which are useful for treating various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to processes for preparing compounds described herein, pharmaceutical compositions containing the disclosed compounds, and the methods for treating diseases mediated through muscarinic receptors.