256369-34-3 Usage
Uses
Used in Pharmaceutical Industry:
3-Azabicyclo[3.1.0]hexan-6-amine 4-methylbenzenesulfonate is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Azabicyclo[3.1.0]hexan-6-amine 4-methylbenzenesulfonate is utilized as a key component in the synthesis of agrochemicals, contributing to the creation of effective pesticides and other agricultural products.
Used in Organic Synthesis:
3-Azabicyclo[3.1.0]hexan-6-amine 4-methylbenzenesulfonate is used as a protecting group in organic synthesis. The 4-methylbenzenesulfonate group helps to block reactive sites on molecules, facilitating the synthesis of complex compounds with greater precision and control.
Used in Chemical Research:
3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate is also employed in chemical research as a valuable tool for exploring new reactions and mechanisms, further expanding the scope of chemical and pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 256369-34-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,6,3,6 and 9 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 256369-34:
(8*2)+(7*5)+(6*6)+(5*3)+(4*6)+(3*9)+(2*3)+(1*4)=163
163 % 10 = 3
So 256369-34-3 is a valid CAS Registry Number.
256369-34-3Relevant academic research and scientific papers
Synthesis of trovafloxacin using various (1α,5α,6α)-3-azabicyclo[3.1.0]hexane derivatives
Norris, Timothy,Braish, Tamim F.,Butters, Michael,DeVries, Keith M.,Hawkins, Joel M.,Massett, Stephen S.,Rose, Peter R.,Santafianos, Dinos,Sklavounos, Constantine
, p. 1615 - 1622 (2007/10/03)
Trovafloxacin, a novel broad spectrum antibacterial, contains the unusual (1α,5α,6α)-3-azabicyclo[3.1.0]hexane ring system. The prototype of the industrial synthesis of this ring system and possible mechanistic pathways to exclusive formation of the exo or 6α-nitro derivative 4 are described, which leads to the key 6a-nitro-3-azabicyclo[3.1.0]hexane intermediate 10. The synthesis of 6a-amino-3-azabicyclo[3.1.0]hexane 16 and useful protected cxo 6-amino derivatives 15 and 17 follows from 10. These can be coupled with the 7-chloronaphthyridone 18 to yield protected trovafloxacin compounds 20-22 in good yield. The ethyl ester of trovafloxacin 21 can also be accessed from the product of coupling 19, derived from 18 and the exo 6-nitro-3-azabicyclo[3.1.0]hexane compound 12. Removal of protecting groups from 20-22 with methanesulfonic acid yields trovafloxacin mesylate from which trovafloxacin zwitterion 1 can be liberated with base treatment. Zwitterion l can also be prepared directly from 16 tosylate salt and naphthyridone-2-carboxylic acid 26. The Royal Society of Chemistry 2000.
