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185563-98-8

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185563-98-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 185563-98-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,5,6 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 185563-98:
(8*1)+(7*8)+(6*5)+(5*5)+(4*6)+(3*3)+(2*9)+(1*8)=178
178 % 10 = 8
So 185563-98-8 is a valid CAS Registry Number.

185563-98-8Downstream Products

185563-98-8Relevant articles and documents

Design and synthesis of a new class of selective integrin α5β1 antagonists

Stragies, Roland,Osterkamp, Frank,Zischinsky, Gunther,Vossmeyer, Doerte,Kalkhof, Holger,Reimer, Ulf,Zahn, Grit

, p. 3786 - 3794 (2008/02/11)

Starting from the structure of integrin αvβ3 in a complex with a peptidic ligand plus SAR data on nonpeptidic ligands, we derived a new class of integrin α5β1 antagonists (1). Several synthesis strategies were applied to evaluate the chemical space around

1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as alpha v beta 3 antagonists

-

, (2008/06/13)

This invention relates to 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles of Formula (I) which are useful as antagonists of alpha v beta 3 and related integrin receptors, to pharmaceutical compositions containing such compounds, alone or in combination with othe

Integrin receptor antagonists

-

, (2008/06/13)

This invention relates to novel heterocycles including 3-?1-?3-(imidazolin-2-ylamino)propyl!indazol-5-ylcarbonylamino!-2-(benzyloxycarbonylamino)propionic acid, which are useful as antagonists of the αv β3 integrin and related cell surface adhesive protein receptors, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of cell adhesion, the treatment of angiogenic disorders, inflammation, bone degradation, cancer metastasis, diabetic retinopathy, thrombosis, restenosis, macular degeneration, and other conditions mediated by cell adhesion and/or cell migration and/or angiogenesis.

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