18559-42-7 Usage
Description
4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid is a chemical compound with the molecular formula C11H10N2O4, belonging to the class of carboxylic acids and a derivative of quinoxaline. It is synthesized through the oxidation of 5,5-dihydroxy-4,4-dimethyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid, resulting in a white to off-white crystalline powder with a molecular weight of 226.21 g/mol. 4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid is of interest in pharmaceutical research due to its structural properties and potential biological activities, which may contribute to the development of new drugs.
Uses
Used in Pharmaceutical Research and Development:
4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique structural properties and potential biological activities make it a valuable candidate for the development of new drugs in the pharmaceutical industry.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid is used as a building block for the design and synthesis of novel therapeutic agents. Its versatile chemical structure allows for the creation of diverse drug candidates with potential applications in treating various diseases and conditions.
Used in Drug Discovery:
4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid is employed as a starting material in drug discovery processes, where its structural features can be modified to generate new compounds with improved pharmacological properties. 4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid serves as a valuable tool in the search for innovative and effective therapeutic agents.
Used in Biochemical Research:
In biochemical research, 4-Methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid is utilized as a probe to study various biological processes and mechanisms. Its interaction with different biomolecules can provide insights into the underlying pathways and help in understanding the molecular basis of diseases, ultimately contributing to the development of targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 18559-42-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,5 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18559-42:
(7*1)+(6*8)+(5*5)+(4*5)+(3*9)+(2*4)+(1*2)=137
137 % 10 = 7
So 18559-42-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O3/c1-12-7-5-3-2-4-6(7)11-8(9(12)13)10(14)15/h2-5H,1H3,(H,14,15)
18559-42-7Relevant articles and documents
Metal-free C3-alkoxycarbonylation of quinoxalin-2(1H)-ones with carbazates as ecofriendly ester sources
Xie, Long-Yong,Peng, Sha,Fan, Tai-Gang,Liu, Yan-Fang,Sun, Meng,Jiang, Li-Lin,Wang, Xing-Xing,Cao, Zhong,He, Wei-Min
, (2019/03/19)
Quinoxaline-3-carboxylates and analogues are prevalent key structural motifs in bioactive natural products and synthetic drugs. However, the practical protocol for preparation of these motifs from simple raw materials under mild conditions remains rare. In this article, we report a facile protocol for the efficient preparation of various quinoxaline-3-carbonyl compounds (30 examples, 63%–92%) through oxidation coupling of quinoxalin-2(1H)-ones with readily available carbazates (or acyl hydrazines) in the presence of K2S2O8 as an oxidant in metal- and base-free conditions. When tert-butyl carbazate was used as the coupling reagent, the decarboxylation product 3-(tert-butyl)-1-methylquinoxalin-2(1H)-one was obtained. The application of this process into a gram-scale synthesis can be easily accomplished. Mechanistic investigations reveal that the functionalization of quinoxalin-2 (1H)-ones via a free-radical pathway.
