185686-39-9Relevant articles and documents
Synthesis of vinyl pyrophosphonate analogues of farnesyl pyrophosphate: New potential inhibitors of farnesyl protein transferase
Zgani, Ibrahim,Menut, Chantal,Monte,ro, Jean Louis
, p. 654 - 661 (2007/10/03)
The synthesis of new bioisosteric analogues of farnesyl pyrophosphate where a vinyl pyrophosphonate replaced the pyrophosphate moiety is described. These compounds have been prepared using a Horner-Wadsworth-Emmons procedure and a modified Michelson react