1857-11-0 Usage
Description
(+)-Sempervirol, a natural product chemical compound isolated from the plant Euphorbia semperflorens, is a diterpenoid with a unique and complex structure. It has been found to possess various biological activities, including anti-inflammatory, anti-tumor, and anti-viral properties, making it a potential candidate for pharmaceutical development. Its pharmacological activities are attributed to its ability to modulate the immune response and inhibit the growth of cancer cells.
Uses
Used in Pharmaceutical Industry:
(+)-Sempervirol is used as a potential therapeutic agent for the treatment of various diseases due to its anti-inflammatory, anti-tumor, and anti-viral properties. Its ability to modulate the immune response and inhibit the growth of cancer cells makes it a promising candidate for pharmaceutical development.
Used in Antiviral Applications:
(+)-Sempervirol is used as an antiviral agent against herpes simplex virus and influenza virus, demonstrating its potential in treating viral infections.
Used in Cancer Treatment:
(+)-Sempervirol is used as an anti-tumor agent, exhibiting inhibitory effects on the growth of cancer cells, making it a potential candidate for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1857-11-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,5 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1857-11:
(6*1)+(5*8)+(4*5)+(3*7)+(2*1)+(1*1)=90
90 % 10 = 0
So 1857-11-0 is a valid CAS Registry Number.
1857-11-0Relevant articles and documents
Chemoenzymatic synthesis of (+)-totarol, (+)-podototarin, (+)-sempervirol, and (+)-jolkinolides E and D
Miyake, Takahiro,Kigoshi, Hideo,Akita, Hiroyuki
, p. 2915 - 2922 (2008/09/17)
The enzymatic resolution products [(1R,4aR,8aR)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-oxo-trans-naphthalene-1-methanol-2-ethylene acetal (8aR)-7 (98% ee) and {acetate of (1S,4aS,8aS)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-oxo-trans-naphthalene-1-methanol-2-ethylene acetal} (8aS)-9 (>99% ee)] obtained by the lipase-catalyzed enantioselective acetylation of (±)-7 in the presence of vinyl acetate as an acyl donor were converted to the α,β-unsaturated ketones (8aR)-6 and (8aS)-6, respectively. Concise syntheses of (+)-totarol 1, (+)-podototarin 2 and (+)-sempervirol 3 were achieved based on Michael reactions between (8aS)-6 and the appropriate β-keto ester followed by aldol condensation. The first chiral syntheses of (+)-jolkinolides E 4 and D 5 were achieved from (5R,10R,12R)-12-hydroxypodocarpa-8(14)-en-13-one 15 derived from (8aR)-6.
